Date published: 2025-12-8

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Calcium ionophore II (CAS 74267-27-9)

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Application:
Calcium ionophore II is A lipophilic ionophore for Ca2+-selective electrodes.
CAS Number:
74267-27-9
Molecular Weight:
460.69
Molecular Formula:
C28H48N2O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Calcium ionophore II is a widely used tool in the field of biochemistry and cell biology, particularly for its ability to transport calcium ions across lipid membranes in a controlled manner. This compound is used in research that aims to understand calcium signaling pathways and the role of calcium as a second messenger within cells. By artificially modulating intracellular calcium levels, scientists are able to study the effects of calcium on cellular processes such as muscle contraction, neurotransmitter release, and enzyme activity. In plant biology, calcium ionophore II is utilized to investigate calcium′s part in regulating plant growth and response to environmental stress. Its use is also critical in the calibration of calcium-sensitive probes, which are essential for the measurement of intracellular calcium concentrations in various experimental setups.


Calcium ionophore II (CAS 74267-27-9) References

  1. Ion-selective electrode for measuring low Ca2+ concentrations in the presence of high K+, Na+ and Mg2+ background.  |  Bedlechowicz-Sliwakowska, I., et al. 2006. Anal Bioanal Chem. 385: 1477-82. PMID: 16847621
  2. Time-dependent phenomena in the potential response of ion-selective electrodes treated by the Nernst-Planck-Poisson model. 1. Intramembrane processes and selectivity.  |  Lingenfelter, P., et al. 2006. Anal Chem. 78: 6783-91. PMID: 17007497
  3. Centrifugal microfluidics with integrated sensing microdome optodes for multiion detection.  |  Watts, AS., et al. 2007. Anal Chem. 79: 8046-54. PMID: 17914753
  4. Ionophore-based ion-exchange emulsions as novel class of complexometric titration reagents.  |  Zhai, J., et al. 2014. Chem Commun (Camb). 50: 12659-61. PMID: 25205536
  5. Enhancing biocompatibility of some cation selective electrodes using heparin modified bacterial cellulose.  |  Badr, IH., et al. 2015. Carbohydr Polym. 134: 687-94. PMID: 26428173
  6. Solvatochromic Dyes as pH-Independent Indicators for Ionophore Nanosphere-Based Complexometric Titrations.  |  Zhai, J., et al. 2015. Anal Chem. 87: 12318-23. PMID: 26595520
  7. Complexometric titrations: new reagents and concepts to overcome old limitations.  |  Zhai, J. and Bakker, E. 2016. Analyst. 141: 4252-61. PMID: 27272695
  8. Continuous Fluorescence Imaging of Intracellular Calcium by Use of Ion-Selective Nanospheres with Adjustable Spectra.  |  Yang, C., et al. 2016. ACS Appl Mater Interfaces. 8: 19892-8. PMID: 27408988
  9. In Vivo Measurement of Calcium Ion with Solid-State Ion-Selective Electrode by Using Shelled Hollow Carbon Nanospheres as a Transducing Layer.  |  Zhao, L., et al. 2019. Anal Chem. 91: 4421-4428. PMID: 30848124
  10. Wearable Organic Electrochemical Transistor Patch for Multiplexed Sensing of Calcium and Ammonium Ions from Human Perspiration.  |  Keene, ST., et al. 2019. Adv Healthc Mater. 8: e1901321. PMID: 31714014
  11. Ionophore-based pH independent detection of ions utilizing aggregation-induced effects.  |  Wang, R., et al. 2020. Analyst. 145: 3846-3850. PMID: 32293619
  12. PLGA microspheres containing plasmid DNA: preservation of supercoiled DNA via cryopreparation and carbohydrate stabilization.  |  Ando, S., et al. 1999. J Pharm Sci. 88: 126-30. PMID: 9874713
  13. Electrochemiluminescence in Luminol-based calcium-selective nanoparticles for the determination of calcium ions  |  J Zhang, Y Chen, D Fang. 2020. Journal of Electroanalytical Chemistry. 878: 114671.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Calcium ionophore II, 50 mg

sc-252541
50 mg
$310.00