C/EBP γ Antibody (S2): sc-517003

C/EBP γ Antibody (S2) is a mouse monoclonal IgG1 kappa light chain antibody that detects C/EBP gamma protein of human origin by western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). Anti-C/EBP gamma antibody (S2) is available as a non-conjugated format. C/EBP gamma protein plays a crucial role in regulating gene expression, particularly in immune response and inflammation. C/EBP gamma protein is primarily located in the nucleus, functioning as a transcription factor by binding to specific DNA sequences to modulate target gene expression. Nuclear localization enables C/EBP gamma protein to directly influence transcriptional machinery, impacting cellular processes like differentiation, proliferation, and apoptosis. C/EBP gamma protein forms heterodimers with other C/EBP family members, such as C/EBP α and C/EBP β, enhancing regulatory capacity and allowing coordinated response to various physiological stimuli. C/EBP gamma protein function and localization studies are essential for understanding its role in health and disease, particularly in conditions with dysregulated immune responses.

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C/EBP γ Antibody (S2) References:

1. Regulation of CCAAT/enhancer-binding protein (C/EBP) activator proteins by heterodimerization with C/EBPgamma (Ig/EBP).  |  Parkin, SE., et al. 2002. J Biol Chem. 277: 23563-72. PMID: 11980905
2. C/EBPdelta and C/EBPgamma bind the CCAAT-box in the human beta-globin promoter and modulate the activity of the CACC-box binding protein, EKLF.  |  Gordon, CT., et al. 2005. Biochim Biophys Acta. 1729: 74-80. PMID: 15833715
3. Regulated expression of three C/EBP isoforms during adipose conversion of 3T3-L1 cells.  |  Cao, Z., et al. 1991. Genes Dev. 5: 1538-52. PMID: 1840554
4. A family of C/EBP-related proteins capable of forming covalently linked leucine zipper dimers in vitro.  |  Williams, SC., et al. 1991. Genes Dev. 5: 1553-67. PMID: 1884998
5. CCAAT-enhancer binding protein: a component of a differentiation switch.  |  Umek, RM., et al. 1991. Science. 251: 288-92. PMID: 1987644
6. Tissue-specific expression, developmental regulation, and genetic mapping of the gene encoding CCAAT/enhancer binding protein.  |  Birkenmeier, EH., et al. 1989. Genes Dev. 3: 1146-56. PMID: 2792758
7. Identification of a rat liver nuclear protein that binds to the enhancer core element of three animal viruses.  |  Johnson, PF., et al. 1987. Genes Dev. 1: 133-46. PMID: 2824279
8. Isolation of a recombinant copy of the gene encoding C/EBP.  |  Landschulz, WH., et al. 1988. Genes Dev. 2: 786-800. PMID: 2850264
9. Cloning of the cDNA encoding human C/EBP gamma, a protein binding to the PRE-I enhancer element of the human interleukin-4 promoter.  |  Davydov, IV., et al. 1995. Gene. 161: 271-5. PMID: 7665092

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-C/EBP γ Antibody (S2) has 5 citations in a variety of scientific publications.

Primary antibodies like Anti-C/EBP γ Antibody (S2) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

C/EBP γ Antibody (S2) Specifications

Alternate Product Name: C/EBP gamma

Product Clone Name: S2

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁ kappa light chain

Amino Acids: 1-150

Epitope Target: C/EBP γ

Epitope Species: human

Product Reactivity/Detection: C/EBP γ

Species Reactivity/Detection: human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, ELISA

Vialing Information: Each vial contains 100 µg IgG₁ kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 5 citations in various scientific publications

Available Conjugates/Forms for C/EBP γ Antibody (S2): N/A