Date published: 2025-12-5

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Boc-OSu (CAS 13139-12-3)

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Alternate Names:
N-(tert-Butoxycarbonyloxy)succinimide; tert-Butyl N-succinimidyl carbonate
Application:
Boc-OSu is A boc-protecting group reagent
CAS Number:
13139-12-3
Purity:
≥98%
Molecular Weight:
215.20
Molecular Formula:
C9H13NO5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Boc-OSu functions as a reagent in peptide synthesis. It acts as a protecting group for the amine group of amino acids, allowing for selective deprotection and subsequent coupling reactions. In the presence of a base, Boc-OSu reacts with the amine group to form a stable carbamate, protecting the amine from unwanted reactions during peptide synthesis. Boc-Osu facilitates the stepwise assembly of peptides by enabling the selective protection and deprotection of amino acid side chains. Boc-OSu′s mechanism of action involves the formation of a covalent bond with the amine group, effectively blocking its reactivity until the deprotection step is initiated. This reagent is useful in the controlled and efficient synthesis of peptides by providing a means to protect specific functional groups, allowing for the precise manipulation of peptide sequences.


Boc-OSu (CAS 13139-12-3) References

  1. Applications of topologically segregated bilayer beads in 'one-bead one-compound' combinatorial libraries.  |  Wang, X., et al. 2005. J Pept Res. 65: 130-8. PMID: 15686543
  2. Peptide and glycopeptide dendrimers and analogous dendrimeric structures and their biomedical applications.  |  Sebestik, J., et al. 2011. Amino Acids. 40: 301-70. PMID: 21058024
  3. Synthesis and characterization of monophosphinic acid DOTA derivative: A smart tool with functionalities for multimodal imaging.  |  Chilla, SNM., et al. 2017. Bioorg Med Chem. 25: 4297-4303. PMID: 28655418

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Boc-OSu, 5 g

sc-252501
5 g
$125.00