BJAB Whole Cell Lysate: sc-2207

The BJAB whole cell lysate is derived from the BJAB cell line, a well-established model derived from human Burkitt's lymphoma, a form of non-Hodgkin's lymphoma that originates from B lymphocytes. This lysate comprises a comprehensive mix of cellular constituents such as proteins, nucleic acids, lipids, and other small molecules, providing a snapshot of the cell's biochemical state under various conditions. Utilizing this lysate, researchers have explored fundamental aspects of B-cell biology, including cellular proliferation, apoptosis, and signal transduction pathways. The BJAB cell line and its lysate have proven especially valuable in the study of B-cell activation and the regulatory mechanisms that control immune responses. In the realm of immunology research, BJAB lysates have facilitated the identification of key proteins and signaling molecules involved in B-cell function and the dysregulation that leads to disease states. By providing a rich source of B-cell-specific molecules, BJAB whole cell lysates enable detailed proteomic and genomic studies, helping to map complex cellular interactions and responses that underlie immune function. This makes the BJAB lysate an indispensable tool in advancing our understanding of immune system dynamics and the molecular biology of lymphocytes.

BJAB Whole Cell Lysate References:

1. Placental oxidative stress in a rat model of preeclampsia.  |  Beausεjour, A., et al. 2007. Placenta. 28: 52-8. PMID: 16469376
2. Apoptosis and molecular pathways in the seminiferous epithelium of aged and photoinhibited Syrian hamsters (Mesocricetus auratus).  |  Morales, E., et al. 2007. J Androl. 28: 123-35. PMID: 16957139