Date published: 2026-4-25

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Biotin-PEG4-Amine (CAS 663171-32-2)

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CAS Number:
663171-32-2
Molecular Weight:
462.61
Molecular Formula:
C20H38N4O6S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Biotin-PEG4-amine is a PEG derivative containing a biotin group and a terminal primary amine group. The amine group can be coupled to carboxyl groups or 5′phosphate groups to form stable amide bonds. The hydrophilic PEG spacer increases solubility in aqueous media and increases membrane impermeability of the molecules conjugated to the biotin compound. It also helps to minimize steric hindrance involved with the binding to avidin molecules.


Biotin-PEG4-Amine (CAS 663171-32-2) References

  1. Unnatural amino acid mutagenesis of GPCRs using amber codon suppression and bioorthogonal labeling.  |  Huber, T., et al. 2013. Methods Enzymol. 520: 281-305. PMID: 23332705
  2. SPECT/NIRF Dual Modality Imaging for Detection of Intraperitoneal Colon Tumor with an Avidin/Biotin Pretargeting System.  |  Dong, C., et al. 2016. Sci Rep. 6: 18905. PMID: 26732543
  3. Multiplex bead binding assays using off-the-shelf components and common flow cytometers.  |  Hattori, T., et al. 2021. J Immunol Methods. 490: 112952. PMID: 33358997

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Biotin-PEG4-Amine, 100 mg

sc-496449
100 mg
$461.00