Molecular structure of Bimatoprost-d4
Bimatoprost-d4
Alternate Names:
17-phenyl trinor PGF2α ethyl amide-d4
Application:
Bimatoprost-d4 is an F-series PG analog. Investigations have shown that bimatoprost is converted by an amidase enzymatic activity in the bovine and human cornea to yield the corresponding free acid, with a conversion rate of about 40 μg/g corneal tissue/24 hours. The free acid, 17-phenyl trinor PGF2α, is a potent FP receptor agonist.
Molecular Weight:
418.6
Molecular Formula:
C25H32D4NO4
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Bimatoprost-d4 (17-phenyl trinor PGF2α ethyl amide-d4) is an F-series PG analog which has been approved for use as an ocular hypotensive drug. Investigations have shown that bimatoprost is converted by an amidase enzymatic activity in the bovine and human cornea to yield the corresponding free acid, with a conversion rate of about 40 μg/g corneal tissue/24 hours. The free acid, 17-phenyl trinor PGF2α, is a potent FP receptor agonist. In human and animal models of glaucoma, FP receptor agonist activity corresponds very closely with intraocular hypotensive activity.
Bimatoprost-d4 References
1 Woodward, D.F., Krauss, A.H., Chen, J., et al. The pharmacology of Bimatoprost (Lumigan™). Survey of Ophthalmology 45 S337-S345 (2001). 2 Sharif, N.A., Williams, G.W., Kelly, C.R. Bimatoprost and its free acid are prostaglandin FP receptor agonists. EOrdering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Bimatoprost-d4, 25 µg | sc-221361 | 25 µg | $101.00 | |||
Bimatoprost-d4, 50 µg | sc-221361A | 50 µg | $190.00 |