BHMT Antibody (3D6): sc-69708
- BHMT Antibody (3D6) is a mouse monoclonal IgG2a, cited in 5 publications, provided at 100 µg/ml
- raised against full length recombinant BHMT of human origin
- recommended for detection of BHMT of mouse, rat and human origin by WB, IP and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for BHMT Antibody (3D6). This work is in progress.
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SEE ALSO...
BHMT Antibody (3D6) is a mouse monoclonal IgG2a antibody that detects betaine-homocysteine methyltransferase (BHMT) in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). BHMT is a crucial zinc-dependent cytosolic enzyme that plays a significant role in the methionine cycle by catalyzing the conversion of betaine and homocysteine into dimethylglycine and methionine, respectively. This enzymatic activity is vital for maintaining proper homocysteine levels in the body, as elevated homocysteine can lead to serious health issues, including cardiovascular and cerebrovascular diseases. BHMT expression is notably high in the liver, where dietary factors such as methionine and choline influence activity levels. In humans, S-adenosylmethionine (SAM) can down-regulate BHMT through NFκB activation, a transcription factor that represses the BHMT gene. Mutations in the BHMT gene can result in hyperhomocysteinemia, a condition characterized by excessive homocysteine levels in the bloodstream, underscoring BHMT′s critical role in metabolic health. Anti-BHMT antibody (3D6) serves as an essential tool for researchers investigating BHMT′s implications in various biological processes and diseases.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
BHMT Antibody (3D6) | sc-69708 | 100 µg/ml | $322.00 |