Molecular structure of β-Estradiol 3-(β-D-glucuronide) sodium salt, CAS Number: 14982-12-8
β-Estradiol 3-(β-D-glucuronide) sodium salt (CAS 14982-12-8)
See product citations (4)
Alternate Names:
1,3,5(10)-Estratriene-3,17β-diol 3-glucuronide; 3,17β-Dihydroxy-1,3,5(10)-estratriene 3-glucuronide
Application:
β-Estradiol 3-(β-D-glucuronide) sodium salt is a non-cholestatic regioisomer of the estrogen metabolite, estradiol 17-(β-D-glucuronide)
CAS Number:
14982-12-8
Purity:
≥98%
Molecular Weight:
470.49
Molecular Formula:
C24H31O8•Na
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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β-Estradiol 3-(β-D-glucuronide) sodium salt is a conjugate formed by combining estradiol with glucuronic acid. It serves as a metabolite of estradiol. Notably, this compound has demonstrated efficacy in wastewater treatment plants for eliminating estrogenic compounds from wastewater. Additionally, it has been validated as a highly sensitive and specific tool for monitoring 17β-estradiol. The improved detection limit provided by this compound enables the monitoring of estrone levels in environmental samples.
β-Estradiol 3-(β-D-glucuronide) sodium salt (CAS 14982-12-8) References
- Human UDP-glucuronosyltransferase UGT2A2: cDNA construction, expression, and functional characterization in comparison with UGT2A1 and UGT2A3. | Sneitz, N., et al. 2009. Pharmacogenet Genomics. 19: 923-34. PMID: 19858781
- The inhibition study of human UDP-glucuronosyltransferases with cytochrome P450 selective substrates and inhibitors. | Liu, Y., et al. 2011. J Enzyme Inhib Med Chem. 26: 386-93. PMID: 20939765
- Quantitation of UGT1A1 in human liver microsomes using stable isotope-labelled peptides and mass spectrometry based proteomic approaches. | Sridar, C., et al. 2013. Xenobiotica. 43: 336-45. PMID: 22943130
- Characterization of the zebrafish Ugt repertoire reveals a new class of drug-metabolizing UDP glucuronosyltransferases. | Wang, Y., et al. 2014. Mol Pharmacol. 86: 62-75. PMID: 24728488
- Regioselective glucuronidation of andrographolide and its major derivatives: metabolite identification, isozyme contribution, and species differences. | Tian, X., et al. 2015. AAPS J. 17: 156-66. PMID: 25204783
- Biomagnification of endocrine disrupting chemicals (EDCs) by Pleuronectes yokohamae: Does P. yokohamae accumulate dietary EDCs? | Nurulnadia, MY., et al. 2016. Chemosphere. 144: 185-92. PMID: 26363319
- An ultrasensitive and selective electrochemical sensor for determination of estrone 3-sulfate sodium salt based on molecularly imprinted polymer modified carbon paste electrode. | Song, H., et al. 2017. Anal Bioanal Chem. 409: 6509-6519. PMID: 28889259
- Design and optimization of the cocktail assay for rapid assessment of the activity of UGT enzymes in human and rat liver microsomes. | Chen, A., et al. 2018. Toxicol Lett. 295: 379-389. PMID: 30036684
- Characterization of function and genetic feature of UDP-glucuronosyltransferase in avian species. | Kawai, YK., et al. 2019. Comp Biochem Physiol C Toxicol Pharmacol. 217: 5-14. PMID: 30476594
- UGT1A1 and UGT1A3 activity and inhibition in human liver and intestinal microsomes and a recombinant UGT system under similar assay conditions using selective substrates and inhibitors. | Mullapudi, TVR., et al. 2021. Xenobiotica. 51: 1236-1246. PMID: 34698602
- The Effect of Single-Walled Carbon Nanotubes on UDP-Glucuronosyltransferase 1A Activity in Human Liver. | Asai, Y., et al. 2022. Biol Pharm Bull. 45: 446-451. PMID: 35370268
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
β-Estradiol 3-(β-D-glucuronide) sodium salt, 5 mg | sc-234876 | 5 mg | $303.00 |