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Benzo[k]fluoranthene (CAS 207-08-9)

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Alternate Names:
Benzo[k]fluoranthene is also known as 11,12-BENZOFLUORANTHENE.
Application:
Benzo[k]fluoranthene is an optical sensor for nitro-aromatic compounds, chosen due to fluorescence quenching of the molecule.
CAS Number:
207-08-9
Purity:
≥97%
Molecular Weight:
252.31
Molecular Formula:
C20H12
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Benzo[k]fluoranthene (BkF) is a polycyclic aromatic hydrocarbon classified as a carcinogen and a mutagen. It may act to induce oxidative stress and cell death, and to interfere with the normal functioning of the immune system. Benzo[k]fluoranthene is a major component of diesel exhaust, cigarette smoke, and other combustion products. It is used as an optical sensor for nitro-aromatic compounds due to its affinity for fluorescence quenching.


Benzo[k]fluoranthene (CAS 207-08-9) References

  1. Mechanisms of arsenite-mediated decreases in benzo[k]fluoranthene-induced human cytochrome P4501A1 levels in HepG2 cells.  |  Bessette, EE., et al. 2005. Drug Metab Dispos. 33: 312-20. PMID: 15576448
  2. Effects of benzo(k)fluoranthene exposure on the biomarkers of scallop Chlamys farreri.  |  Pan, L., et al. 2005. Comp Biochem Physiol C Toxicol Pharmacol. 141: 248-56. PMID: 16095977
  3. Responses of antioxidant systems and LPO level to benzo(a)pyrene and benzo(k)fluoranthene in the haemolymph of the scallop Chlamys ferrari.  |  Pan, LQ., et al. 2006. Environ Pollut. 141: 443-51. PMID: 16271429
  4. In vivo and in vitro immunosuppressive effects of benzo[k]fluoranthene in female Balb/c mice.  |  Jeon, TW., et al. 2005. J Toxicol Environ Health A. 68: 2033-50. PMID: 16326422
  5. Induction of CYP1A1 and CYP1B1 by benzo(k)fluoranthene and benzo(a)pyrene in T-47D human breast cancer cells: roles of PAH interactions and PAH metabolites.  |  Spink, DC., et al. 2008. Toxicol Appl Pharmacol. 226: 213-24. PMID: 17919675
  6. Multiwalled carbon nanotubes as adsorbents of solid-phase extraction for determination of polycyclic aromatic hydrocarbons in environmental waters coupled with high-performance liquid chromatography.  |  Wang, WD., et al. 2007. J Chromatogr A. 1173: 27-36. PMID: 17977550
  7. Influence of humic acid on bioavailability and toxicity of benzo[k]fluoranthene to Japanese medaka.  |  Chen, S., et al. 2008. Environ Sci Technol. 42: 9431-6. PMID: 19174927
  8. Synthesis, structures, and physical properties of benzo[k]fluoranthene-based linear acenes.  |  Kung, YH., et al. 2010. Chemistry. 16: 5909-19. PMID: 20397154
  9. Optical absorption and emission properties of fluoranthene, benzo[k]fluoranthene, and their derivatives. A DFT study.  |  Saranya, G., et al. 2011. J Phys Chem A. 115: 14647-56. PMID: 22077554
  10. Heterogeneous reactions of particulate benzo[b]fluoranthene and benzo[k]fluoranthene with NO(3) radicals.  |  Zhang, P., et al. 2014. Chemosphere. 99: 34-40. PMID: 24210551
  11. Benzo[a]pyrene and Benzo[k]fluoranthene in some processed fish and fish products.  |  Olatunji, OS., et al. 2015. Int J Environ Res Public Health. 12: 940-51. PMID: 25607603
  12. Biomarker responses in zebrafish (Danio rerio) following long-term exposure to microplastic-associated chlorpyrifos and benzo(k)fluoranthene.  |  Hanslik, L., et al. 2022. Aquat Toxicol. 245: 106120. PMID: 35183844
  13. Identification of mutagenic dihydrodiols as metabolites of benzo(j)fluoranthene and benzo(k)fluoranthene.  |  LaVoie, EJ., et al. 1980. Cancer Res. 40: 4528-32. PMID: 7002294
  14. Tumour initiating activity of dihydrodiols of benzo[b]fluoranthene, benzo[j]fluoranthene, and benzo[k]fluoranthene.  |  LaVoie, EJ., et al. 1982. Carcinogenesis. 3: 49-52. PMID: 7067037
  15. Fluorescence Quenching Of Benzo[K]Fluoranthene In Poly(Vinyl Alcohol) Film: A Possible Optical Sensor For Nitro Aromatic Compounds  |  Digambara Patra and A.K. Mishra. 2001. Sensors And Actuators B: Chemical. 80: 278-282.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Benzo[k]fluoranthene, 100 mg

sc-214585
100 mg
$205.00