Benzocaine N-β-D-Glucoside (CAS 28315-50-6)

Benzocaine N-β-D-Glucoside is a chemically modified version of benzocaine, a well-known ester local anesthetic, where a β-D-glucoside moiety is attached to the nitrogen atom of the parent compound. This glycosylation significantly impacts the compound′s physical and chemical properties, particularly enhancing its solubility in aqueous solutions and potentially modifying its interaction with biological membranes. The introduction of a glucoside group is a strategic modification used in research to study how sugar attachments influence drug bioavailability and metabolism. In biochemical research, Benzocaine N-β-D-Glucoside serves as a valuable tool for investigating the role of glycosylation in drug transport and stability, as well as its effects on the pharmacokinetic profiles of local anesthetics. The glycosylated derivative could potentially offer insights into targeted delivery mechanisms, where enzyme-specific cleavage in the body might selectively activate or deactivate the compound′s anesthetic properties. Researchers utilize this compound to explore innovative approaches in drug design, focusing on how structural modifications can lead to changes in the duration and efficacy of action, thereby contributing to fundamental advancements in the understanding of molecular interactions within biological systems.