ARMC8 Antibody (E-1): sc-365307
- ARMC8 Antibody (E-1) is a mouse monoclonal IgG1 λ ARMC8 antibody, cited in 5 publications, provided at 200 µg/ml
- raised against amino acids 311-610 mapping within an internal region of ARMC8 of human origin
- ARMC8 Antibody (E-1) is recommended for detection of ARMC8 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- Anti-ARMC8 Antibody (E-1) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgGλ BP-HRP (mouse IgGλ binding protein-HRP) is the preferred secondary detection reagent for ARMC8 Antibody (E-1) for WB and IHC(P) applications. This reagent is now offered in a bundle with ARMC8 Antibody (E-1) (see ordering information below). For additional m-IgGλ BP conjugates see our complete list of Mouse IgG Binding Proteins.
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ARMC8 Antibody (E-1) is a mouse monoclonal IgG1 antibody that detects ARMC8 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). ARMC8 (E-1) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. ARMC8, also known as armadillo repeat containing 8, is a 673 amino acid protein characterized by the presence of 14 armadillo repeats, which are critical for signal transduction. ARMC8 is involved in essential cellular processes such as cell migration, proliferation, and tissue maintenance, while playing a significant role in tumorigenesis. Multiple isoforms of ARMC8, resulting from alternative splicing, highlight functional diversity and adaptability in various cellular contexts. ARMC8 is encoded on human chromosome 3, a region rich in genes associated with cancer and other critical biological functions. Understanding ARMC8 interactions with specific proteins can provide insights into cellular signaling pathways and potential disease mechanisms, making anti-ARMC8 antibody (E-1) a valuable research tool.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
ARMC8 Antibody (E-1) References:
- Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. | Zhang, QH., et al. 2000. Genome Res. 10: 1546-60. PMID: 11042152
- [New tumor suppressor genes in hot spots of human chromosome 3: new methods of identification]. | Braga, EA., et al. 2003. Mol Biol (Mosk). 37: 194-211. PMID: 12723467
- Plasticity of human chromosome 3 during primate evolution. | Tsend-Ayush, E., et al. 2004. Genomics. 83: 193-202. PMID: 14706448
- Genomic structure and paralogous regions of the inversion breakpoint occurring between human chromosome 3p12.3 and orangutan chromosome 2. | Yue, Y., et al. 2005. Cytogenet Genome Res. 108: 98-105. PMID: 15545721
- Comparative cytogenetics of human chromosome 3q21.3 reveals a hot spot for ectopic recombination in hominoid evolution. | Yue, Y., et al. 2005. Genomics. 85: 36-47. PMID: 15607420
- Evolutionarily plastic regions at human 3p21.3 coincide with tumor breakpoints identified by the 'elimination test'. | Darai, E., et al. 2005. Genomics. 86: 1-12. PMID: 15913951
- The DNA sequence, annotation and analysis of human chromosome 3. | Muzny, DM., et al. 2006. Nature. 440: 1194-8. PMID: 16641997
- RanBPM, Muskelin, p48EMLP, p44CTLH, and the armadillo-repeat proteins ARMC8alpha and ARMC8beta are components of the CTLH complex. | Kobayashi, N., et al. 2007. Gene. 396: 236-47. PMID: 17467196
- Proteasome-dependent degradation of alpha-catenin is regulated by interaction with ARMc8alpha. | Suzuki, T., et al. 2008. Biochem J. 411: 581-91. PMID: 18215130
- Armc8 regulates the invasive ability of hepatocellular carcinoma through E-cadherin/catenin complex. | Zhao, Y., et al. 2016. Tumour Biol. 37: 11219-24. PMID: 26944057
- ARMc8: a potential diagnostic and therapeutic target for cancers. | Zhou, D., et al. 2016. Hum Pathol. 54: 201. PMID: 27036312
- Downregulation of ARMC8 promotes tumorigenesis through activating Wnt/β-catenin pathway and EMT in cutaneous squamous cell carcinomas. | Li, X., et al. 2021. J Dermatol Sci. 102: 184-192. PMID: 34016486
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ARMC8 Antibody (E-1) | sc-365307 | 200 µg/ml | $322.00 | |||
ARMC8 Antibody (E-1): m-IgGλ BP-HRP Bundle | sc-522199 | 200 µg Ab, 40 µg BP | $361.00 | |||
ARMC8 Antibody (E-1) AC | sc-365307 AC | 500 µg/ml, 25% agarose | $424.00 | |||
ARMC8 Antibody (E-1) HRP | sc-365307 HRP | 200 µg/ml | $322.00 | |||
ARMC8 Antibody (E-1) FITC | sc-365307 FITC | 200 µg/ml | $336.00 | |||
ARMC8 Antibody (E-1) PE | sc-365307 PE | 200 µg/ml | $349.00 | |||
ARMC8 Antibody (E-1) Alexa Fluor® 488 | sc-365307 AF488 | 200 µg/ml | $364.00 | |||
ARMC8 Antibody (E-1) Alexa Fluor® 546 | sc-365307 AF546 | 200 µg/ml | $364.00 | |||
ARMC8 Antibody (E-1) Alexa Fluor® 594 | sc-365307 AF594 | 200 µg/ml | $364.00 | |||
ARMC8 Antibody (E-1) Alexa Fluor® 647 | sc-365307 AF647 | 200 µg/ml | $364.00 | |||
ARMC8 Antibody (E-1) Alexa Fluor® 680 | sc-365307 AF680 | 200 µg/ml | $364.00 | |||
ARMC8 Antibody (E-1) Alexa Fluor® 790 | sc-365307 AF790 | 200 µg/ml | $364.00 |