Molecular structure of Arachidonoyl-N-methyl amide, CAS Number: 156910-29-1
Arachidonoyl-N-methyl amide (CAS 156910-29-1)
Application:
Arachidonoyl-N-methyl amide is a cell-cell communication inhibitor
CAS Number:
156910-29-1
Molecular Weight:
317.51
Molecular Formula:
C21H35NO
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Anandamide (AEA) is an endogenous cannabinoid that binds to both central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors. The biological actions of AEA are terminated by cellular uptake and hydrolysis of the amide bond by the enzyme fatty acid amide hydrolase. This compound is an analog of AEA that binds to the human CB1 receptor with a Ki of 60 nM.1 It inhibits rat glial gap junction cell-cell communication 100% at a concentration of 50 µM.2
Arachidonoyl-N-methyl amide (CAS 156910-29-1) References
- Arachidonic acid amide inhibitors of gap junction cell-cell communication. | Boger, DL., et al. 1999. Bioorg Med Chem Lett. 9: 1151-4. PMID: 10328303
- The Secreted Enzyme PM20D1 Regulates Lipidated Amino Acid Uncouplers of Mitochondria. | Long, JZ., et al. 2016. Cell. 166: 424-435. PMID: 27374330
- Structural requirements for binding of anandamide-type compounds to the brain cannabinoid receptor. | Sheskin, T., et al. 1997. J Med Chem. 40: 659-67. PMID: 9057852
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Arachidonoyl-N-methyl amide, 5 mg | sc-205212 | 5 mg | $42.00 | |||
Arachidonoyl-N-methyl amide, 10 mg | sc-205212A | 10 mg | $81.00 |