MF: C9H14N2O2·HCl MW: 218.68 A selective agonist of α7 AChRs.
Protein-Interacting Inhibitors, Activators & Substrates
AChR α 7 Activators
AR-R17779 HCl (CAS 178419-47-1)
C 9H 14N 2O 2·HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use. *
Certificate of Analysis for lot specific data (including water content).
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AR-R17779 HCl is a selective agonist of α7 AChRs (K
i values are 190 and 16000 nM for rat α7 and α4β2 receptors, respectively).
Soluble in DMSO (50 mM).
Store at room temperature
411.7° C at 760 mmHg (Predicted)
20 D 1.59 (Predicted)
α20/D -62.7°, c = 1 in methanol
5050 = 420 nM (human); Neuronal acetylcholine receptor protein alpha-7 subunit: EC 5050 = 21 µM (rat)
i= 92 nM (human); α7 receptor : K i= 190 nM (rat); α4β2 receptors : K i= 16 µM (rat)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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