AMI-193 (CAS 510-74-7)
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AMI-193 is an intriguing azaspiro compound with a distinctive structure. It comprises 1,3,8-triazaspiro[4.5]decan-4-one as its core, featuring a phenyl group attached to N-1 and a 3-(4-fluorophenoxy)propyl group attached to N-8. This compound acts as a selective antagonist for 5-HT receptors, specifically binding to 5-HT2 sites with comparable potency to spiperone while exhibiting lower affinity for 5-HT2C receptors. Furthermore, it functions as a high-affinity antagonist for D2 receptors (with a Ki value of 3 nM). Notably, AMI-193 lacks the behavioral disruption effects observed with spiperone. In terms of its chemical classification, AMI-193 falls under the category of azaspiro compounds, as well as organofluorine compounds. It also exhibits characteristics of an aromatic ether, a tertiary amino compound, and belongs to the family of piperidines.
AMI-193 (CAS 510-74-7) References
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Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
AMI-193, 10 mg | sc-203509 | 10 mg | $129.00 | |||
AMI-193, 50 mg | sc-203509A | 50 mg | $548.00 |