Molecular structure of AM 1172, CAS Number: 251908-92-6
AM 1172 (CAS 251908-92-6)
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Alternate Names:
AM679; AM2201-d5; AM2201
Application:
AM 1172 is a potent and selective inhibitor of anandamide uptake and FAAH
CAS Number:
251908-92-6
Molecular Weight:
409.6
Molecular Formula:
C27H39NO2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
AM 1172 is a potent and selective inhibitor of anandamide uptake, resistant to FAAH (fatty acid amide hydrolase) hydrolysis. Metabolically stable "reversed" isomer of AM 404 (sc-200363). AM 1172 is an inhibitor of FAAH. AM 1172 is an activator of CB1 and CB2.
AM 1172 (CAS 251908-92-6) References
- Anandamide transport is independent of fatty-acid amide hydrolase activity and is blocked by the hydrolysis-resistant inhibitor AM1172. | Fegley, D., et al. 2004. Proc Natl Acad Sci U S A. 101: 8756-61. PMID: 15138300
- The endocannabinoid system: physiology and pharmacology. | Rodríguez de Fonseca, F., et al. 2005. Alcohol Alcohol. 40: 2-14. PMID: 15550444
- Regulation of brain reward by the endocannabinoid system: a critical review of behavioral studies in animals. | Vlachou, S. and Panagis, G. 2014. Curr Pharm Des. 20: 2072-88. PMID: 23829366
- Retrospective analysis of synthetic cannabinoids in serum samples--epidemiology and consumption patterns. | Jaenicke, NJ., et al. 2014. Forensic Sci Int. 242: 81-87. PMID: 25050839
- Arvanil, olvanil, AM 1172 and LY 2183240 (various cannabinoid CB1 receptor agonists) increase the threshold for maximal electroshock-induced seizures in mice. | Tutka, P., et al. 2018. Pharmacol Rep. 70: 106-109. PMID: 29335158
- The e-Psychonauts' 'Spiced' World; Assessment of the Synthetic Cannabinoids' Information Available Online. | Zangani, C., et al. 2020. Curr Neuropharmacol. 18: 966-1051. PMID: 32116194
- Distribution of the Cannabinoid Receptor Type 1 in the Brain of the Genetically Audiogenic Seizure-Prone Hamster GASH/Sal. | Fuerte-Hortigón, A., et al. 2021. Front Behav Neurosci. 15: 613798. PMID: 33841106
- Exploration of Multiverse Activities of Endocannabinoids in Biological Systems. | Behl, T., et al. 2022. Int J Mol Sci. 23: PMID: 35628545
Inhibitor of:
FAAH.Activator of:
CB1, and CB2.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
AM 1172, 10 mg | sc-202456 | 10 mg | $200.00 | |||
AM 1172, 50 mg | sc-202456A | 50 mg | $650.00 |