(αR)-α-[(2,3,4,6-Tetra-O-acetyl-β-D-glucopyranosyl)oxy]benzeneacetamide (CAS 207512-68-3)

(αR)-α-[(2,3,4,6-Tetra-O-acetyl-β-D-glucopyranosyl)oxy]benzeneacetamide, a compound synthesized from benzeneacetamide and 2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl chloride, has found widespread application in biochemical research, particularly in the investigation of carbohydrate-protein interactions and glycosylation processes. Due to its glycosyl moiety, this compound serves as a glycosylation reagent in the synthesis of glycopeptides, glycoproteins, and glycolipids. The acetyl groups attached to the glucopyranosyl unit protect its hydroxyl groups during chemical synthesis, allowing for selective glycosylation at desired positions. Additionally, (αR)-α-[(2,3,4,6-Tetra-O-acetyl-β-D-glucopyranosyl)oxy]benzeneacetamide acts as a glycosyl donor in glycosylation reactions catalyzed by glycosyltransferases, enzymes involved in the biosynthesis of complex carbohydrates and glycoconjugates. Through glycosylation studies using this compound, researchers gain insights into the substrate specificity and catalytic mechanisms of glycosyltransferases, as well as the role of glycosylation in various biological processes such as cell signaling, adhesion, and immune response. Furthermore, this chemical is instrumental in the preparation of carbohydrate microarrays and glycan libraries for high-throughput screening of carbohydrate-protein interactions, contributing to the development of diagnostic tools and agents targeting glycan-mediated biological events.