alpha Synuclein (h): 293T Lysate: sc-111729

α-Synuclein (h): 293T Lysate is derived from the 293T cell line, a human embryonic kidney cell line genetically modified to express the SV40 large T antigen, which enhances its transfection efficiency and protein production capabilities. This lysate is specifically enriched with human α-synuclein, a presynaptic neuronal protein that plays a critical role in synaptic function and neurotransmitter release. α-Synuclein is known for its ability to bind to lipid membranes and vesicles, influencing synaptic vesicle trafficking and recycling. In research, α-Synuclein (h): 293T Lysate is utilized to study the biochemical properties and cellular functions of α-synuclein. Researchers employ this lysate in Western blotting to detect and quantify α-synuclein expression under various experimental conditions, providing insights into its regulation and post-translational modifications. The lysate is also used in co-immunoprecipitation assays to identify protein-protein interactions involving α-synuclein, which helps explain its role in cellular signaling pathways and synaptic function. Additionally, this lysate is valuable in assays designed to study the aggregation properties of α-synuclein, as it can form amyloid-like fibrils under certain conditions. Such studies contribute to understanding the mechanisms of protein aggregation and its impact on cellular processes. The use of α-Synuclein (h): 293T Lysate allows researchers to investigate the molecular mechanisms underlying synaptic function and protein aggregation, offering valuable insights into basic neuronal biology. The origin and quality of the 293T cell line are meticulously controlled, ensuring consistent and reproducible results in experimental research focused on synaptic and cellular protein functions.