α-lactalbumin Antibody (0.N.14): sc-58672

α-lactalbumin Antibody (0.N.14) is a mouse monoclonal IgM antibody that detects α-lactalbumin in human samples through applications such as western blotting (WB), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). α-lactalbumin plays a crucial role in lactose synthesis in the mammary gland, functioning as a regulatory protein that aids in milk production and contributes to neonatal immune defense through antimicrobial properties. α-lactalbumin is secreted by mammary epithelial cells and elevates calcium levels while inducing apoptosis selectively in transformed and lymphoid cells, sparing mature epithelial cells. Such selective cytotoxicity suggests α-lactalbumin may help maintain mucosal immunity by regulating lymphocyte and epithelial cell functions. The human form of α-lactalbumin consists of 123 amino acid residues, and gene regulation is influenced by a highly conserved region in the 5′ flanking sequences, which may play a significant role in hormonal control and tissue-specific expression of milk protein genes in the mammary gland. α-lactalbumin (0.N.14) antibody serves as an invaluable tool for researchers investigating the multifaceted roles of α-lactalbumin in both lactation and immune response, as well as potential implications in breast cancer research.

The preferred α-lactalbumin antibody is α-lactalbumin Antibody (H-1): sc-393900.