AKR7A Antibody (E-11): sc-365400
- AKR7A Antibody (E-11) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 335-359 at the C-terminus of AKR7A2 of human origin
- recommended for detection of AKR7A2, AKR7A3 and AKR7A4 of human origin, AKR7A5 of mouse origin and AKR7A2 of rat origin by WB, IP, IF, IHC(P) and ELISA
- m-IgG1 BP-HRP is the preferred secondary detection reagent for AKR7A Antibody (E-11) for WB and IHC(P) applications. This reagent is now offered in a bundle with AKR7A Antibody (E-11) (see ordering information below).
AKR7A Antibody (E-11) is a mouse monoclonal IgG1 antibody that detects aldo-keto reductase 7A (AKR7A) in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). AKR7A plays a crucial role in the metabolism of dicarbonyl compounds, particularly in the detoxification of environmental carcinogens such as Aflatoxin B1, which is significant for maintaining cellular health and preventing cancer development. AKR7A is predominantly expressed in the liver, where constitutive expression is vital for the elimination of harmful metabolites, thereby acting as an endogenous chemo-preventative agent. Additionally, the AKR7A gene is located on human chromosome 1p36.13, a region often associated with deletions in sporadic colorectal cancer, highlighting AKR7A′s importance in cancer biology. AKR7A forms homodimers, particularly in tissues such as the kidney, colon, pancreas, and endometrium, further underscoring functional versatility and relevance in various physiological and pathological processes. With broad species reactivity and multiple applications, anti-AKR7A antibody (E-11) serves as an essential tool for researchers investigating AKR7A′s role in metabolism and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
AKR7A Antibody (E-11) | sc-365400 | 200 µg/ml | $322.00 | |||
AKR7A Antibody (E-11): m-IgG1 BP-HRP Bundle | sc-552009 | 200 µg Ab; 20 µg BP | $361.00 | |||
AKR7A (E-11) Neutralizing Peptide | sc-365400 P | 100 µg/0.5 ml | $69.00 |