ADAMTS-14 Antibody (G-8): sc-373773
- ADAMTS-14 Antibody (G-8) is a mouse monoclonal IgG1 κ ADAMTS-14 antibody provided at 200 µg/ml
- raised against amino acids 1086-1223 mapping at the C-terminus of ADAMTS-14 of human origin
- ADAMTS-14 Antibody (G-8) is recommended for detection of ADAMTS-14 of human origin by WB, IP, IF and ELISA
- Anti-ADAMTS-14 Antibody (G-8) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgGκ BP-HRP is the preferred secondary detection reagent for ADAMTS-14 Antibody (G-8) for WB applications. This reagent is now offered in a bundle with ADAMTS-14 Antibody (G-8) (see ordering information below). For additional m-IgGκ BP conjugates see our complete list of Mouse IgG Binding Proteins.
ADAMTS-14 Antibody (G-8) is a mouse monoclonal IgG1 kappa light chain antibody that detects ADAMTS-14 protein of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). ADAMTS-14 (G-8) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. ADAMTS-14, a member of the ADAMTS (a disintegrin and metalloproteinase domain with Thrombospondin type-1 modules) family, plays a crucial role in regulating extracellular matrix components, particularly in collagen turnover, which is vital for maintaining tissue integrity and function. ADAMTS-14 is predominantly located in collagen-rich tissues, such as cartilage, where ADAMTS-14 is involved in remodeling processes essential for normal physiological functions and in the pathogenesis of diseases like arthritis. ADAMTS-14′s unique structure, characterized by four thrombospondin type-1 motifs, allows ADAMTS-14 to interact with various substrates and other proteins, influencing cellular signaling pathways and tissue homeostasis. Using anti-ADAMTS-14 antibody (G-8) in research can provide valuable insights into this important protease′s role in both health and disease.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
ADAMTS-14 Antibody (G-8) References:
- ADAMTS: a novel family of proteases with an ADAM protease domain and thrombospondin 1 repeats. | Tang, BL. and Hong, W. 1999. FEBS Lett. 445: 223-5. PMID: 10094461
- ADAMTS: a novel family of extracellular matrix proteases. | Tang, BL. 2001. Int J Biochem Cell Biol. 33: 33-44. PMID: 11167130
- Cloning and characterization of ADAMTS-14, a novel ADAMTS displaying high homology with ADAMTS-2 and ADAMTS-3. | Colige, A., et al. 2002. J Biol Chem. 277: 5756-66. PMID: 11741898
- Cloning, expression analysis, and structural characterization of seven novel human ADAMTSs, a family of metalloproteinases with disintegrin and thrombospondin-1 domains. | Cal, S., et al. 2002. Gene. 283: 49-62. PMID: 11867212
- Expression profiling of metalloproteinases and their inhibitors in cartilage. | Kevorkian, L., et al. 2004. Arthritis Rheum. 50: 131-41. PMID: 14730609
- Genetic association between polymorphisms in the ADAMTS14 gene and multiple sclerosis. | Goertsches, R., et al. 2005. J Neuroimmunol. 164: 140-7. PMID: 15913795
- A complete expression profile of matrix-degrading metalloproteinases in Dupuytren's disease. | Johnston, P., et al. 2007. J Hand Surg Am. 32: 343-51. PMID: 17336841
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ADAMTS-14 Antibody (G-8) | sc-373773 | 200 µg/ml | $316.00 | |||
ADAMTS-14 Antibody (G-8): m-IgGκ BP-HRP Bundle | sc-522494 | 200 µg Ab, 40 µg BP | $354.00 | |||
ADAMTS-14 Antibody (G-8) AC | sc-373773 AC | 500 µg/ml, 25% agarose | $416.00 | |||
ADAMTS-14 Antibody (G-8) HRP | sc-373773 HRP | 200 µg/ml | $316.00 | |||
ADAMTS-14 Antibody (G-8) FITC | sc-373773 FITC | 200 µg/ml | $330.00 | |||
ADAMTS-14 Antibody (G-8) PE | sc-373773 PE | 200 µg/ml | $343.00 | |||
ADAMTS-14 Antibody (G-8) Alexa Fluor® 488 | sc-373773 AF488 | 200 µg/ml | $357.00 | |||
ADAMTS-14 Antibody (G-8) Alexa Fluor® 546 | sc-373773 AF546 | 200 µg/ml | $357.00 | |||
ADAMTS-14 Antibody (G-8) Alexa Fluor® 594 | sc-373773 AF594 | 200 µg/ml | $357.00 | |||
ADAMTS-14 Antibody (G-8) Alexa Fluor® 647 | sc-373773 AF647 | 200 µg/ml | $357.00 | |||
ADAMTS-14 Antibody (G-8) Alexa Fluor® 680 | sc-373773 AF680 | 200 µg/ml | $357.00 | |||
ADAMTS-14 Antibody (G-8) Alexa Fluor® 790 | sc-373773 AF790 | 200 µg/ml | $357.00 |