Nicotinic Acetylcholine Receptor gamma/delta/CHRNG/CHRND Antibody (7): sc-65758
- Nicotinic Acetylcholine Receptor gamma/delta/CHRNG/CHRND Antibody (7) is a rat monoclonal IgG1 provided at 200 µg/ml
- raised against denatured, purified AChR of Torpedo origin
- recommended for detection of nicotinic AChRγ/δ of Torpedo, Xenopus, Rana and canine origin by IP
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Nicotinic Acetylcholine Receptor gamma/delta/CHRNG/CHRND Antibody (7). This work is in progress.
AChRγ/δ Antibody (7) is a rat monoclonal IgG1 antibody that detects AChRγ/δ in Torpedo, Xenopus, Rana, and canine species by immunoprecipitation (IP). AChRγ and AChRδ are integral members of the nicotinic acetylcholine receptor family, which plays a crucial role in neuromuscular transmission and synaptic plasticity. These receptors are primarily located at the postsynaptic membrane of the neuromuscular junction, where they facilitate rapid signal transmission by allowing ions to flow through their transmembrane aqueous pore upon binding with acetylcholine. The proper functioning of AChRγ and AChRδ is vital for muscle contraction and overall motor function, as these receptors mediate excitatory signals necessary for muscle activation. Mutations in genes encoding AChRγ and AChRδ can lead to severe neuromuscular disorders, such as Escobar syndrome and congenital myasthenic syndromes, highlighting their significance in both health and disease. Anti-AChRγ/δ antibody (7) serves as an essential tool for researchers studying neuromuscular junction dynamics and underlying mechanisms of related pathologies, providing insights into molecular interactions and modifications that govern receptor function.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Nicotinic Acetylcholine Receptor gamma/delta/CHRNG/CHRND Antibody (7) | sc-65758 | 200 µg/ml | $316.00 |