Nicotinic Acetylcholine Receptor gamma/CHRNG Antibody (165): sc-65798
- Nicotinic Acetylcholine Receptor gamma/CHRNG Antibody (165) is a rat monoclonal IgG2a provided at 200 µg/ml
- raised against denatured, purified AChR of Torpedo origin
- recommended for detection of nicotinic AChRγ of Torpedo origin by WB and IF
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Nicotinic Acetylcholine Receptor gamma/CHRNG Antibody (165). This work is in progress.
AChRγ Antibody (165) is a rat monoclonal IgG2a antibody that detects AChRγ in Torpedo species through western blotting (WB) and immunofluorescence (IF). AChRγ is a crucial member of the acetylcholine receptor family, consisting of 517 amino acids, and plays a significant role in ligand binding and neuromuscular organogenesis. Anti-AChRγ antibody (165) is essential for studying the formation and maintenance of neuromuscular junctions, where AChRγ facilitates signal transmission between nerves and muscles. AChRγ is involved in the assembly of the receptor complex, which is critical for responding to acetylcholine. Mutations in the gene encoding AChRγ can lead to severe developmental disorders, such as Escobar syndrome and a lethal form of multiple pterygium syndrome, highlighting AChRγ′s importance in both normal physiology and disease. AChRγ (165) monoclonal antibody serves as an invaluable tool for researchers studying neuromuscular junctions and related pathologies, providing insights into the molecular mechanisms underlying these critical biological processes.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Nicotinic Acetylcholine Receptor gamma/CHRNG Antibody (165) | sc-65798 | 200 µg/ml | $316.00 |