Date published: 2026-3-18

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Abietic acid (CAS 514-10-3)

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Alternate Names:
Rosin Acid; Sylvic Acid
CAS Number:
514-10-3
Purity:
>70%
Molecular Weight:
302.45
Molecular Formula:
C20H30O2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Abietic acid is a compound extensively studied in the field of organic chemistry and materials science for its role as a precursor in the synthesis of various resin acids and its natural occurrence in pine resin. Researchers investigate abietic acid for its potential to modify the properties of alkyd resins, which are used in the production of varnishes and paints. It is also a subject of study in the development of bio-based polymers, where its incorporation can lead to materials with improved performance and environmental sustainability. In analytical chemistry, abietic acid is used as a reference compound for the characterization of plant resins and for understanding the chemical composition of aged wood products. Additionally, its photostability and oxidation reactions are of interest in the preservation and restoration of cultural heritage objects, as abietic acid-based materials are often found in historical artifacts.


Abietic acid (CAS 514-10-3) References

  1. Abietic acid attenuates allergic airway inflammation in a mouse allergic asthma model.  |  Gao, Y., et al. 2016. Int Immunopharmacol. 38: 261-6. PMID: 27318791
  2. Abietic acid isolated from pine resin (Resina Pini) enhances angiogenesis in HUVECs and accelerates cutaneous wound healing in mice.  |  Park, JY., et al. 2017. J Ethnopharmacol. 203: 279-287. PMID: 28389357
  3. Abietic acid attenuates IL-1β-induced inflammation in human osteoarthritis chondrocytes.  |  Kang, S., et al. 2018. Int Immunopharmacol. 64: 110-115. PMID: 30172103
  4. Abietic acid suppresses non-small-cell lung cancer cell growth via blocking IKKβ/NF-κB signaling.  |  Liu, X., et al. 2019. Onco Targets Ther. 12: 4825-4837. PMID: 31354305
  5. Antimicrobial and antibiofilm effects of abietic acid on cariogenic Streptococcus mutans.  |  Ito, Y., et al. 2020. Odontology. 108: 57-65. PMID: 31520265
  6. Synergistic Effect of Abietic Acid with Oxacillin against Methicillin-Resistant Staphylococcus pseudintermedius.  |  Buommino, E., et al. 2021. Antibiotics (Basel). 10: PMID: 33467635
  7. Abietic acid ameliorates psoriasis-like inflammation and modulates gut microbiota in mice.  |  Li, XQ., et al. 2021. J Ethnopharmacol. 272: 113934. PMID: 33607198
  8. Abietic acid alleviates endoplasmic reticulum stress and lipid accumulation in human primary hepatocytes through the AMPK/ORP150 signaling.  |  Jung, TW., et al. 2022. Biochem Biophys Res Commun. 608: 142-148. PMID: 35398611
  9. Eco-friendly adsorbents based on abietic acid, boswellic acid, and chitosan/magnetite for removing waste oil from the surface of the water.  |  Fekry, M., et al. 2022. Environ Sci Pollut Res Int. 29: 64633-64646. PMID: 35474426
  10. Abietic acid attenuates sepsis-induced lung injury by inhibiting nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) pathway to inhibit M1 macrophage polarization.  |  Fang, H., et al. 2022. Exp Anim. 71: 481-490. PMID: 35644586
  11. Abietic acid ameliorates nephropathy progression via mitigating renal oxidative stress, inflammation, fibrosis and apoptosis in high fat diet and low dose streptozotocin-induced diabetic rats.  |  Wahab, NAA., et al. 2022. Phytomedicine. 107: 154464. PMID: 36215789
  12. Abietic acid induces ferroptosis via the activation of the HO-1 pathway in bladder cancer cells.  |  Xu, Y., et al. 2023. Biomed Pharmacother. 158: 114154. PMID: 36584429
  13. Abietic acid inhibits acetaminophen-induced liver injury by alleviating inflammation and ferroptosis through regulating Nrf2/HO-1 axis.  |  An, Y., et al. 2023. Int Immunopharmacol. 118: 110029. PMID: 36963265

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Abietic acid, 25 g

sc-252346
25 g
$100.00