Abacavir Triphosphate TEA Salt (CAS 137820-58-7 (free acid))
Alternate Names:
P-[[(2S,4R)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopenten-1-yl]methyl]ester Triphosphate TEA Salt
Application:
Abacavir Triphosphate TEA Salt is a nucleoside reverse transcriptase inhibitor (NRTI)
CAS Number:
137820-58-7 (free acid)
Molecular Weight:
526.27
Molecular Formula:
C14H21N6O10P3•xC6H16N
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
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SDS & Certificate of Analysis
Abacavir Triphosphate Trisodium Salt is a metabolite of Abacavir [also called Ziagen (sc-338739)], a nucleoside reverse transcriptase inhibitor (NRTI). NRTIs work by blocking HIV reverse transcriptase (HIV-1 RT), an HIV enzyme.
Abacavir Triphosphate TEA Salt (CAS 137820-58-7 (free acid)) References
- Association between presence of HLA-B*5701, HLA-DR7, and HLA-DQ3 and hypersensitivity to HIV-1 reverse-transcriptase inhibitor abacavir. | Mallal, S., et al. 2002. Lancet. 359: 727-32. PMID: 11888582
- Prospective genetic screening decreases the incidence of abacavir hypersensitivity reactions in the Western Australian HIV cohort study. | Rauch, A., et al. 2006. Clin Infect Dis. 43: 99-102. PMID: 16758424
- Prospective screening for human leukocyte antigen-B*5701 avoids abacavir hypersensitivity reaction in the ethnically mixed French HIV population. | Zucman, D., et al. 2007. J Acquir Immune Defic Syndr. 45: 1-3. PMID: 17356469
- HLA-B*5701 screening for hypersensitivity to abacavir. | Mallal, S., et al. 2008. N Engl J Med. 358: 568-79. PMID: 18256392
Inhibitor of:
HIV-1 RT.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Abacavir Triphosphate TEA Salt, 1 mg | sc-479386 | 1 mg | $448.00 |