A 839977 CAS: 870061-27-1
MF: C19H14Cl2N6O
MW: 413.26
A potent antagonist P2X7.

A 839977 (CAS 870061-27-1)

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Synonym: 1-(2,3-Dichlorophenyl)-N-[[2-(2-pyridinyloxy)phenyl]methyl]-1H-tetrazol-5-amine; 1-(2,3-Dichlorophenyl)-N-[2-(2-pyridinyloxy)benzyl]-1H-tetrazol-5-amine
Application: A potent antagonist P2X7
CAS Number: 870061-27-1
Molecular Weight: 413.26
Molecular Formula: C19H14Cl2N6O
* Refer to Certificate of Analysis for lot specific data (including water content).
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A 839977 is a potent P2X7 antagonist that blocks BzATP-evoked calcium influx at P2X7 receptors. This compound displays antinociceptive properties in rat and mice models of inflammatory pain.

Physical State :
Solid
Solubility :
Soluble in DMSO (100 mM).
Storage :
Store at 4° C
Boiling Point :
~604.9° C at 760 mmHg (Predicted)
Density :
~1.5 g/cm3 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
53325875
MDL Number :
MFCD19690959
SMILES :
C1=CC=C(C(=C1)CNC2=NN=NN2C3=C(C(=CC=C3)Cl)Cl)OC4=CC=CC=N4

Download SDS (MSDS)

Certificate of Analysis

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