8-Nitroguanine-4,8-13C2-7-15N (CAS 1215708-85-2)
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8-Nitroguanine-4,8-13C2-7-15N is a modified form of guanine that is to study DNA damage and mutagenesis. It is incorporated into DNA during replication and can lead to base mispairing, causing mutations. This modified nucleotide can be used to investigate the effects of nitrosative stress on DNA and its potential role in carcinogenesis. 8-Nitroguanine-4,8-13C2-7-15N is also utilized in studies to understand the molecular mechanisms of DNA repair and the cellular response to oxidative and nitrosative damage. Its presence in DNA can be detected and quantified using various analytical techniques, allowing assessment of the extent of DNA damage and its implications for genomic stability. In experimental applications, this modified nucleotide serves for investigating the molecular pathways involved in DNA damage and repair processes, providing insights into the underlying mechanisms of mutagenesis.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
8-Nitroguanine-4,8-13C2-7-15N, 250 µg | sc-217508 | 250 µg | $490.00 |