8-Hydroxy Carvedilol (CAS 159426-95-6)
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8-Hydroxy Carvedilol is a metabolite of Carvedilol, a compound that is recognized for its utility in research on biochemical pathways involving adrenergic receptors. In non-clinical studies, 8-Hydroxy Carvedilol is used to understand the metabolism of Carvedilol, as well as to identify the enzymes responsible for its biotransformation. The compound′s interactions with various cytochrome P450 isoforms are of particular interest, providing insights into chemical metabolism and the factors that influence it. Moreover, the kinetics of 8-Hydroxy Carvedilol are studied to ascertain how it is distributed, metabolized, and eliminated in biological systems. In addition, research into the antioxidant properties of 8-Hydroxy Carvedilol contributes to a deeper understanding of the role that metabolites may play in oxidative stress within cells.
8-Hydroxy Carvedilol (CAS 159426-95-6) References
- Antihypertensive drugs metabolism: an update to pharmacokinetic profiles and computational approaches. | Zisaki, A., et al. 2015. Curr Pharm Des. 21: 806-22. PMID: 25341854
- Low-volume LC-MS/MS method for the pharmacokinetic investigation of carvedilol, enalapril and their metabolites in whole blood and plasma: Application to a paediatric clinical trial. | Gangnus, T., et al. 2021. Drug Test Anal. 13: 694-708. PMID: 33126289
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
8-Hydroxy Carvedilol, 2.5 mg | sc-490057 | 2.5 mg | $1300.00 | |||
8-Hydroxy Carvedilol, 2.5 mg | sc-490057-CW | 2.5 mg | $1600.00 |