![(7R,8S,9R,10S)-rel-7,8,9,10-Tetrahydrobenzo[a]pyrene-7,8,9,10-tetrol (CAS 61490-66-2) - chemical structure image](https://media.scbt.com/product/7r-8s-9r-10s-rel-7-8-9-10-tetrahydrobenzoapyrene-7-8-9-10-tetrol-61490-66-2-structure_32_10_b_321014.jpg)
![(7R,8S,9R,10S)-rel-7,8,9,10-Tetrahydrobenzo[a]pyrene-7,8,9,10-tetrol (CAS 61490-66-2) - chemical structure image](https://media.scbt.com/product/7r-8s-9r-10s-rel-7-8-9-10-tetrahydrobenzoapyrene-7-8-9-10-tetrol-61490-66-2-structure_32_10_t_321014.jpg "Molecular structure of (7R,8S,9R,10S)-rel-7,8,9,10-Tetrahydrobenzo[a]pyrene-7,8,9,10-tetrol, CAS Number: 61490-66-2")
Molecular structure of (7R,8S,9R,10S)-rel-7,8,9,10-Tetrahydrobenzo[a]pyrene-7,8,9,10-tetrol, CAS Number: 61490-66-2
(7R,8S,9R,10S)-rel-7,8,9,10-Tetrahydrobenzo[a]pyrene-7,8,9,10-tetrol (CAS 61490-66-2)
Alternate Names:
Benzo[a]pyrenetetrol; Tetrol I 1
Application:
(7R,8S,9R,10S)-rel-7,8,9,10-Tetrahydrobenzo[a]pyrene-7,8,9,10-tetrol is an environmental pollutant and known carcinogen
CAS Number:
61490-66-2
Molecular Weight:
320.34
Molecular Formula:
C20H16O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
(7R,8S,9R,10S)-rel-7,8,9,10-Tetrahydrobenzo[a]pyrene-7,8,9,10-tetrol is a known human and rat carcinogen present as an environmental pollutant. (7R,8S,9R,10S)-rel-7,8,9,10-Tetrahydrobenzo[a]pyrene-7,8,9,10-tetrol is also used in metabolic studies.
(7R,8S,9R,10S)-rel-7,8,9,10-Tetrahydrobenzo[a]pyrene-7,8,9,10-tetrol (CAS 61490-66-2) References
- Myeloperoxidase--463A variant reduces benzo[a]pyrene diol epoxide DNA adducts in skin of coal tar treated patients. | Rojas, M., et al. 2001. Carcinogenesis. 22: 1015-8. PMID: 11408343
- In vivo formation of (+)-anti-benzo[a]pyrene diol-epoxide-plasma albumin adducts in fish. | Padrós, J. and Pelletier, E. 2000. Mar Environ Res. 50: 347-51. PMID: 11460716
- Characterization of tetrol I-1 and (+/-)-anti-BPDE-DNA adducts with solid-matrix fluorescence quenching. | Smith, BW. and Hurtubise, RJ. 2003. Appl Spectrosc. 57: 943-9. PMID: 14661837
- GSTM1 null genotype as a risk factor for anti-BPDE-DNA adduct formation in mononuclear white blood cells of coke-oven workers. | Pavanello, S., et al. 2004. Mutat Res. 558: 53-62. PMID: 15036119
- Solid-matrix fluorescence quenching of benzo[e]pyrene and (+/-)-anti-dibenzo[a, l]pyrene diolepoxide-DNA adducts. | Thompson, AL. and Hurtubise, RJ. 2005. Appl Spectrosc. 59: 126-33. PMID: 15720748
- Separation and detection of a benzo[a]pyrene metabolite with capillary electrophoresis in the presence of DNA using laser-induced fluorescence. | Marlow, M. and Hurtubise, RJ. 2002. Talanta. 57: 193-201. PMID: 18968619
- Importance of CYP1A1 and CYP1B1 in bioactivation of benzo[a]pyrene in human lung cell lines. | Uppstad, H., et al. 2010. Toxicol Lett. 192: 221-8. PMID: 19879933
- B(a)P adduct levels and fertility: A cross‑sectional study in a Sicilian population. | Oliveri Conti, G., et al. 2017. Mol Med Rep. 15: 3398-3404. PMID: 28350051
- Comparison of the solid-matrix luminescence properties and photophysical parameters of two products from benzo(a)pyrene-DNA adducts. | Chu, Y. and Hurtubise, RJ. 1994. Photochem Photobiol. 59: 603-10. PMID: 8066119
- Comparison of 32P-postlabeling and HPLC-FD analysis of DNA adducts in rats acutely exposed to benzo(a)pyrene. | Godschalk, RW., et al. 1997. Chem Biol Interact. 104: 41-54. PMID: 9158694
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
(7R,8S,9R,10S)-rel-7,8,9,10-Tetrahydrobenzo[a]pyrene-7,8,9,10-tetrol, 0.5 mg | sc-474274 | 0.5 mg | $423.00 | |||
(7R,8S,9R,10S)-rel-7,8,9,10-Tetrahydrobenzo[a]pyrene-7,8,9,10-tetrol, 0.5 mg | sc-474274-CW | 0.5 mg | $714.00 |