Date published: 2025-12-1

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6-O-(tert-Butyldimethylsilyl)-D-glucal (CAS 58871-09-3)

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CAS Number:
58871-09-3
Molecular Weight:
260.40
Molecular Formula:
C12H24O4Si
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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6-O-(tert-Butyldimethylsilyl)-D-glucal is a chemical compound that has been extensively studied in scientific research, particularly in the fields of organic chemistry and carbohydrate chemistry. This compound is a derivative of D-glucal, a cyclic sugar derivative that serves as a versatile building block in organic synthesis. 6-O-(tert-Butyldimethylsilyl)-D-glucal is commonly used as a precursor for the synthesis of various carbohydrate derivatives and complex organic molecules. Its tert-butyldimethylsilyl (TBS) protecting group provides stability during synthetic transformations and facilitates selective functionalization at the hydroxyl group position. By selectively removing the TBS group under mild conditions, researchers can access the free hydroxyl group for further chemical modifications. Moreover, 6-O-(tert-Butyldimethylsilyl)-D-glucal serves as a valuable substrate for stereoselective reactions, such as glycosylation and cross-coupling reactions, enabling the construction of diverse carbohydrate-based structures with high stereochemical precision. Its use in organic synthesis has contributed to the development of new methodologies for the efficient assembly of complex molecules and the synthesis of bioactive natural products. Overall, 6-O-(tert-Butyldimethylsilyl)-D-glucal is a valuable tool in scientific research for carbohydrate synthesis and organic chemistry. Its versatility and synthetic utility make it indispensable for the preparation of diverse carbohydrate derivatives and structurally complex molecules, driving advances in chemical synthesis and molecular design.


6-O-(tert-Butyldimethylsilyl)-D-glucal (CAS 58871-09-3) References

  1. Adducts of uridine and glycals as potential substrates for glycosyltransferases.  |  Wandzik, I. and Bieg, T. 2007. Bioorg Chem. 35: 401-16. PMID: 17707879

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

6-O-(tert-Butyldimethylsilyl)-D-glucal, 250 mg

sc-256999
250 mg
$126.00