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6-Monodeoxy-6-monoamino-β-cyclodextrin (CAS 126927-47-7)

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Alternate Names:
6-Monodeoxy-6-monoamino-beta-cyclodextrin hydrochloride
CAS Number:
126927-47-7
Molecular Weight:
1170.46
Molecular Formula:
C42H72O34NCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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6-Monodeoxy-6-monoamino-β-cyclodextrin is a functionalized β-cyclodextrin derivative widely used in chemical, materials, and supramolecular chemistry research. The amino substitution at the 6-position provides a reactive site for chemical conjugation while preserving the characteristic host-guest binding properties of the cyclodextrin cavity. This compound is commonly employed for the covalent attachment of polymers, fluorophores, ligands, biomolecules, and surface modifiers, making it a valuable tool for studying molecular recognition, molecular encapsulation, and host-guest interactions. It is also used as a building block in the development of supramolecular assemblies, stimuli-responsive materials, molecular machines, and functional sensors for analytical research. Due to its versatile chemical reactivity and inclusion complex-forming ability, 6-Monodeoxy-6-monoamino-β-cyclodextrin is an important reagent for the synthesis and characterization of advanced cyclodextrin-based materials and conjugates for research applications.


6-Monodeoxy-6-monoamino-β-cyclodextrin (CAS 126927-47-7) References

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  2. Ester hydrolysis by a cyclodextrin dimer catalyst with a metallophenanthroline linking group.  |  Zhou, YH., et al. 2008. Chemistry. 14: 7193-201. PMID: 18601233
  3. Bioadhesive properties and biodistribution of cyclodextrin-poly(anhydride) nanoparticles.  |  Agüeros, M., et al. 2009. Eur J Pharm Sci. 37: 231-40. PMID: 19491010
  4. Ester hydrolysis by a cyclodextrin dimer catalyst with a tridentate N,N',N''-zinc linking group.  |  Tang, SP., et al. 2009. Chem Asian J. 4: 1354-60. PMID: 19579255
  5. Increased oral bioavailability of paclitaxel by its encapsulation through complex formation with cyclodextrins in poly(anhydride) nanoparticles.  |  Agüeros, M., et al. 2010. J Control Release. 145: 2-8. PMID: 20347897
  6. Beta-cyclodextrin/surface plasmon resonance detection system for sensing bitter-astringent taste intensity of green tea catechins.  |  Hayashi, N., et al. 2010. J Agric Food Chem. 58: 8351-6. PMID: 20572674
  7. Optimized alkylated cyclodextrin polysulphates with reduced risks on thromboembolic accidents improve osteoarthritic chondrocyte metabolism.  |  Groeneboer, S., et al. 2011. Rheumatology (Oxford). 50: 1226-35. PMID: 21345936
  8. Generalized model of electromigration with 1:1 (analyte:selector) complexation stoichiometry: part II. Application to dual systems and experimental verification.  |  Müllerová, L., et al. 2015. J Chromatogr A. 1384: 147-54. PMID: 25666498
  9. Injectable Glycol Chitosan Hydrogel Containing Folic Acid-Functionalized Cyclodextrin-Paclitaxel Complex for Breast Cancer Therapy.  |  Hyun, H., et al. 2021. Nanomaterials (Basel). 11: PMID: 33513732
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Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

6-Monodeoxy-6-monoamino-β-cyclodextrin, 1 g

sc-300036
1 g
$1375.00