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6-Bromoandrostenedione (CAS 38632-00-7)

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Alternate Names:
6β-Bromo Androstenedione; (6β)-6-Bromoandrost-4-ene-3,17-dione
Application:
6-Bromoandrostenedione is An androstenedione analog and aromatase inhibitor.
CAS Number:
38632-00-7
Molecular Weight:
365.31
Molecular Formula:
C19H25BrO2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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6-Bromoandrostenedione (6-BAD) is a derivative of androstenedione, a naturally occurring steroid hormone, and is a prohormone of testosterone. It is an aromatase inhibitor and increases levels of testosterone. This affects muscle growth and development, behavior, cognition, and motor function. 6-Bromoandrostenedione also increases levels of other hormones, such as growth hormone, insulin-like growth factor 1 (IGF-1), and erythropoietin (EPO). Additionally, it may act to have beneficial effects on cardiovascular health and the immune system. Researchers primarily use 6-Bromoandrostenedione to study the effects of testosterone.


6-Bromoandrostenedione (CAS 38632-00-7) References

  1. Aromatase inhibitors: past, present and future.  |  Séralini, G. and Moslemi, S. 2001. Mol Cell Endocrinol. 178: 117-31. PMID: 11403901
  2. Synthesis and biochemical properties of 6-bromoandrostenedione derivatives with a 2,2-dimethyl or 2-methyl group as aromatase inhibitors.  |  Numazawa, M., et al. 2004. Biol Pharm Bull. 27: 1878-82. PMID: 15516742
  3. Benign Synthesis of Thiazolo-androstenone Derivatives as Potent Anticancer Agents.  |  Ali, MA., et al. 2018. Org Lett. 20: 5927-5932. PMID: 30204455
  4. Hexafluoroisopropanol-Mediated Domino Reaction for the Synthesis of Thiazolo-androstenones: Potent Anticancer Agents.  |  Okolo, C., et al. 2018. ACS Omega. 3: 17991-18001. PMID: 30613817
  5. Synthetic and Medicinal Perspective of Fused-Thiazoles as Anticancer Agents.  |  Pawar, S., et al. 2021. Anticancer Agents Med Chem. 21: 1379-1402. PMID: 32723259
  6. Benign Synthesis of Fused-thiazoles with Enone-based Natural Products and Drugs for Lead Discovery.  |  Alnufaie, R., et al. 2021. New J Chem. 45: 6001-6017. PMID: 33840994
  7. Domino/Cascade and Multicomponent Reactions for the Synthesis of Thiazole Derivatives.  |  Alam, MA. 2022. Curr Org Chem. 26: 343-347. PMID: 35936384
  8. The aromatase active site: the C-6 'front' side of the androgen molecule is required for binding.  |  Tan, L. and Rousseau, P. 1987. Biochem Biophys Res Commun. 147: 1259-67. PMID: 3663216
  9. Estrogen synthesis in human breast tumor and its inhibition by testololactone and bromoandrostenedione.  |  Dao, TL. 1982. Cancer Res. 42: 3338s-3341s. PMID: 7083197
  10. Inhibition of estrogen synthesis in human breast tumors by testololactone and bromoandrostenedione.  |  Budnick, RM. and Dao, TL. 1980. Steroids. 35: 533-41. PMID: 7394858
  11. Green chemistry approaches for thiazole containing compounds as a potential scaffold for cancer therapy  |  Sharma, D., Sharma, V., Sharma, A., Goyal, R., Tonk, R. K., Thakur, V. K., & Sharma, P. C. 2021. Sustainable Chemistry and Pharmacy. 23: 100496.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

6-Bromoandrostenedione, 10 mg

sc-207138
10 mg
$367.00