Molecular structure of 5α-Cholest-7-en-3β-ol, CAS Number: 80-99-9
5α-Cholest-7-en-3β-ol (CAS 80-99-9)
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Alternate Names:
Lathosterol; 3β-Hydroxy-5α,7-cholestene
Application:
5α-Cholest-7-en-3β-ol is used as a substrate in enzymatic assay for plasma cholesterol
CAS Number:
80-99-9
Purity:
≥98%
Molecular Weight:
386.65
Molecular Formula:
C27H46O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
5α-Cholest-7-en-3β-ol is an intermediate in cholesterol biosynthesis pathway. 5α-Cholest-7-en-3β-ol in serum is carried on lipoproteins and is indicative of the rate of cholesterol synthesis. It acts as a marker of synthesis of cholesterol and is not affected by dietary consumption of cholesterol.
5α-Cholest-7-en-3β-ol (CAS 80-99-9) References
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- Deuterated delta 7-cholestenol analogues as mechanistic probes for wild-type and mutated delta 7-sterol-C5(6)-desaturase. | Rahier, A. 2001. Biochemistry. 40: 256-67. PMID: 11141078
- The distribution of free sterols, polyhydroxysteroids and steroid glycosides in various body components of the starfish Patiria (=Asterina) pectinifera. | Kicha, AA., et al. 2001. Comp Biochem Physiol B Biochem Mol Biol. 128: 43-52. PMID: 11163303
- The conversion of cholest-5-en-3beta-ol into cholest-7-en-3beta-ol by the echinoderms Asterias rubens and Solaster papposus. | Smith, AG. and Goad, LJ. 1975. Biochem J. 146: 35-40. PMID: 1147903
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- Molecular characterization of the microsomal tamoxifen binding site. | Kedjouar, B., et al. 2004. J Biol Chem. 279: 34048-61. PMID: 15175332
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- Sterol composition and biosynthesis in mouse salivary glands. | Hindy, AM., et al. 1986. Arch Oral Biol. 31: 87-93. PMID: 3460541
- In vitro leishmanicidal activity of two cholesterol derivatives. | Isaac-Márquez, AP. and Lezama-Dávila, CM. 2022. World J Microbiol Biotechnol. 38: 66. PMID: 35246768
- Sterol biosynthesis in vitro of rat renal inner medulla. | Bojesen, E., et al. 1973. Biochim Biophys Acta. 306: 237-48. PMID: 4713153
- The sterols of the echinoderm Asterias rubens. | Smith, AG., et al. 1973. Biochem J. 135: 443-55. PMID: 4772271
- Transformation of 5 alpha-cholest-7-en-3 beta-ol to cholesterol and cholestanol in cerebrotendinous xanthomatosis. | Tint, GS. and Salen, G. 1974. J Lipid Res. 15: 256-62. PMID: 4827915
- The biological conversion of 5alpha-cholest-8-en-3beta-ol to 5alpha-cholest-7-en-3beta-ol in the biosynthesis of cholesterol. | Canonica, L., et al. 1968. Steroids. 11: 287-98. PMID: 5642322
- Sterol composition of bovine retinal rod outer segment membranes and whole retinas. | Fliesler, SJ. and Schroepfer, GJ. 1982. Biochim Biophys Acta. 711: 138-48. PMID: 7066367
- Sterol metabolism. XLII. On the interception of singlet molecular oxygen by sterols. | Smith, LL. and Stroud, JP. 1978. Photochem Photobiol. 28: 479-85. PMID: 733929
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
5α-Cholest-7-en-3β-ol, 25 mg | sc-210429 | 25 mg | $117.00 | |||
5α-Cholest-7-en-3β-ol, 100 mg | sc-210429A | 100 mg | $372.00 |