5-Hydroxypyrazinecarboxamide (CAS 13924-96-4)

5-Hydroxypyrazinecarboxamide is a chemical compound characterized by its incorporation of a pyrazine ring—a six-membered heterocyclic ring containing nitrogen atoms at positions 1 and 4—modified by hydroxyl and carboxamide functional groups. This structure confers distinct chemical properties, including increased polarity and potential for hydrogen bonding, which are critical in its interactions at the molecular level. While not used clinically, this compound has found a niche in various research domains, particularly in the study of heterocyclic chemistry and as a potential intermediate in the synthesis of more complex biochemical compounds. The specific mechanism of action of 5-hydroxypyrazinecarboxamide involves its role as a building block in synthesizing ligands that can chelate metal ions, making it valuable in studies related to metalloenzymes and metal-mediated catalysis. In research contexts, this chemical′s ability to bind metals can be exploited to explore metal ion interactions in biological systems, offering insights into enzyme mechanisms that depend on metal cofactors. Additionally, its structural motif is useful in materials science for developing novel organic compounds with specific electronic or photonic properties. These applications highlight its versatility and importance in fundamental research that aims to explore and manipulate molecular interactions and reactions.