Date published: 2026-4-28

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5-Hydroxy-Imidacloprid (CAS 380912-09-4)

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Alternate Names:
5-Hydroxy-Imidacloprid is known as a metabolite of Imidacloprid.
Application:
5-Hydroxy-Imidacloprid is a metabolite of Imidacloprid, a neonicotinoid found in certain neuro-active insecticides.
CAS Number:
380912-09-4
Molecular Weight:
271.66
Molecular Formula:
C9H10ClN5O3
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

5-Hydroxy-Imidacloprid is a metabolite of Imidacloprid, a neonicotinoid found in certain neuro-active insecticides. 5-Hydroxy-Imidacloprid is a water-soluble insecticide that has been utilized in research to investigate the impact of neonicotinoid insecticides on insect nervous systems. Moreover, it has been employed to explore the biochemical and physiological consequences of neonicotinoids on plants.


5-Hydroxy-Imidacloprid (CAS 380912-09-4) References

  1. Effects of imidacloprid metabolites on habituation in honeybees suggest the existence of two subtypes of nicotinic receptors differentially expressed during adult development.  |  Guez, D., et al. 2003. Pharmacol Biochem Behav. 75: 217-22. PMID: 12759130
  2. In vivo distribution and metabolisation of 14C-imidacloprid in different compartments of Apis mellifera L.  |  Suchail, S., et al. 2004. Pest Manag Sci. 60: 1056-62. PMID: 15532678
  3. Different utilizable substrates have different effects on cometabolic fate of imidacloprid in Stenotrophomonas maltophilia.  |  Liu, Z., et al. 2013. Appl Microbiol Biotechnol. 97: 6537-47. PMID: 23053094
  4. Biochemical mechanisms of imidacloprid resistance in Nilaparvata lugens: over-expression of cytochrome P450 CYP6AY1.  |  Ding, Z., et al. 2013. Insect Biochem Mol Biol. 43: 1021-7. PMID: 23994173
  5. Trace level determination of pyrethroid and neonicotinoid insecticides in beebread using acetonitrile-based extraction followed by analysis with ultra-high-performance liquid chromatography-tandem mass spectrometry.  |  Giroud, B., et al. 2013. J Chromatogr A. 1316: 53-61. PMID: 24120025
  6. Imidacloprid is degraded by CYP353D1v2, a cytochrome P450 overexpressed in a resistant strain of Laodelphax striatellus.  |  Elzaki, MEA., et al. 2017. Pest Manag Sci. 73: 1358-1363. PMID: 28296046
  7. A liquid chromatography with tandem mass spectrometry method to simultaneously determinate chlorpyrifos, imidacloprid and imidacloprid metabolites in wheat.  |  Huang, M., et al. 2019. J Sep Sci. 42: 1210-1221. PMID: 30653273
  8. Neural conduction, visual motion detection, and insect flight behaviour are disrupted by low doses of imidacloprid and its metabolites.  |  Parkinson, RH. and Gray, JR. 2019. Neurotoxicology. 72: 107-113. PMID: 30790592
  9. Exposure to neonicotinoid insecticides in the U.S. general population: Data from the 2015-2016 national health and nutrition examination survey.  |  Ospina, M., et al. 2019. Environ Res. 176: 108555. PMID: 31288196
  10. In vitro metabolism of imidacloprid and acetamiprid in rainbow trout and rat.  |  Kolanczyk, RC., et al. 2020. Xenobiotica. 50: 805-814. PMID: 31724896
  11. Oligotrophic bacterium Hymenobacter latericoloratus CGMCC 16346 degrades the neonicotinoid imidacloprid in surface water.  |  Guo, L., et al. 2020. AMB Express. 10: 7. PMID: 31939001
  12. Associations of neonicotinoids with insulin and glucose homeostasis parameters in US adults: NHANES 2015-2016.  |  Vuong, AM., et al. 2022. Chemosphere. 286: 131642. PMID: 34351280
  13. An integrated approach, based on mass spectrometry, for the assessment of imidacloprid metabolism and penetration into mouse brain and fetus after oral treatment.  |  Passoni, A., et al. 2021. Toxicology. 462: 152935. PMID: 34509577

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

5-Hydroxy-Imidacloprid, 1 mg

sc-490571
1 mg
$354.00

5-Hydroxy-Imidacloprid, 1 mg

sc-490571-CW
1 mg
$510.00

5-Hydroxy-Imidacloprid, 10 mg

sc-490571A
10 mg
$1248.00

5-Hydroxy-Imidacloprid, 25 mg

sc-490571B
25 mg
$2497.00

5-Hydroxy-Imidacloprid, 50 mg

sc-490571C
50 mg
$5046.00

5-Hydroxy-Imidacloprid, 100 mg

sc-490571D
100 mg
$9364.00