Date published: 2025-9-26

1-800-457-3801

SCBT Portrait Logo
Seach Input

5-Ethynyl-1-methyl-1H-imidazole (CAS 71759-92-7)

0.0(0)
Write a reviewAsk a question

Application:
5-Ethynyl-1-methyl-1H-imidazole is a heterocyclic building block
CAS Number:
71759-92-7
Molecular Weight:
106.13
Molecular Formula:
C6H6N2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

The versatile compound known as 5-Ethynyl-1-methyl-1H-imidazole holds widespread significance in scientific research, particularly in the realms of chemistry, biochemistry, and medicine. Its diverse applications span various laboratory experiments, serving as a fundamental reagent in the synthesis of compounds like amino acids and peptides. Within the field of biochemistry, researchers rely on 5-Ethynyl-1-methyl-1H-imidazole to unravel the intricate structures and functions of proteins and other vital biomolecules. Additionally, it plays a pivotal role in studying enzyme kinetics and drug metabolism. Although the exact mechanism remains elusive, this compound is believed to engage in interactions with diverse proteins, biomolecules, and potentially hormones within the cellular environment.


5-Ethynyl-1-methyl-1H-imidazole (CAS 71759-92-7) References

  1. Synthesis and biological evaluation of glycal-derived novel tetrahydrofuran 1,2,3-triazoles by 'click' chemistry.  |  Vijaya Raghava Reddy, L., et al. 2010. Carbohydr Res. 345: 1515-21. PMID: 20478557
  2. Sequential one-pot ruthenium-catalyzed azide-alkyne cycloaddition from primary alkyl halides and sodium azide.  |  Johansson, JR., et al. 2011. J Org Chem. 76: 2355-9. PMID: 21388208
  3. HIF-1α inhibitors: synthesis and biological evaluation of novel moracin O and P analogues.  |  Xia, Y., et al. 2011. Eur J Med Chem. 46: 2386-96. PMID: 21481991
  4. Design and synthesis of neuroprotective methylthiazoles and modification as NO-chimeras for neurodegenerative therapy.  |  Qin, Z., et al. 2012. J Med Chem. 55: 6784-801. PMID: 22779770
  5. Novel acyclic phosphonylated 1,2,3-triazolonucleosides with an acetamidomethyl linker: synthesis and biological activity.  |  Głowacka, IE., et al. 2014. Arch Pharm (Weinheim). 347: 506-14. PMID: 24664932
  6. Synthesis and structure-activity relationship studies of conformationally flexible tetrahydroisoquinolinyl triazole carboxamide and triazole substituted benzamide analogues as σ2 receptor ligands.  |  Bai, S., et al. 2014. J Med Chem. 57: 4239-51. PMID: 24821398
  7. Lead optimization of a pyrazole sulfonamide series of Trypanosoma brucei N-myristoyltransferase inhibitors: identification and evaluation of CNS penetrant compounds as potential treatments for stage 2 human African trypanosomiasis.  |  Brand, S., et al. 2014. J Med Chem. 57: 9855-69. PMID: 25412409
  8. PEGylated N-Heterocyclic Carbene Anchors Designed To Stabilize Gold Nanoparticles in Biologically Relevant Media.  |  MacLeod, MJ. and Johnson, JA. 2015. J Am Chem Soc. 137: 7974-7. PMID: 26081724
  9. Mitochondria-Targeting Anticancer Metal Complexes.  |  Erxleben, A. 2019. Curr Med Chem. 26: 694-728. PMID: 29521200
  10. Selective Imaging of Lipids in Adipocytes by Using an Imidazolyl Derivative of Perylene Bisimide.  |  Mishra, R., et al. 2018. Chembiochem. 19: 1386-1390. PMID: 29624834
  11. Robust gold nanorods stabilized by bidentate N-heterocyclic-carbene-thiolate ligands.  |  MacLeod, MJ., et al. 2019. Nat Chem. 11: 57-63. PMID: 30420777
  12. Pyrazole-Based Lactate Dehydrogenase Inhibitors with Optimized Cell Activity and Pharmacokinetic Properties.  |  Rai, G., et al. 2020. J Med Chem. 63: 10984-11011. PMID: 32902275
  13. Square-Planar vs. Trigonal Bipyramidal Geometry in Pt(II) Complexes Containing Triazole-Based Glucose Ligands as Potential Anticancer Agents.  |  Annunziata, A., et al. 2021. Int J Mol Sci. 22: PMID: 34445409

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

5-Ethynyl-1-methyl-1H-imidazole, 1 g

sc-233352
1 g
$465.00