Date published: 2026-1-31

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4-(Trifluoromethyl)benzoyl fluoride (CAS 368-94-5)

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CAS Number:
368-94-5
Molecular Weight:
192.11
Molecular Formula:
C8H4F4O
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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4-(Trifluoromethyl)benzoyl fluoride (TFBF) is primarily used in the synthesis of various organic compounds and has found applications in several fields of research such as materials science and environmental science. Its unique properties make it an excellent reagent for the preparation of fluorine-containing compounds. 4-(Trifluoromethyl)benzoyl fluoride is a highly reactive compound that reacts with various functional groups such as alcohols, amines, and thiols. It is used as a fluorinating agent due to its ability to introduce fluorine into organic molecules. The mechanism of action of 4-(Trifluoromethyl)benzoyl fluoride involves the formation of a covalent bond between the fluoride ion and the functional group of the organic molecule. Additionally, studies have shown that 4-(Trifluoromethyl)benzoyl fluoride is a potent inhibitor of acetylcholinesterase, the enzyme responsible for breaking down the neurotransmitter acetylcholine, and also exhibits antifungal activity against various fungal strains.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

4-(Trifluoromethyl)benzoyl fluoride, 1 g

sc-261537
1 g
$196.00