Date published: 2026-3-8

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4-Methyl-1,3-dioxane (CAS 1120-97-4)

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CAS Number:
1120-97-4
Molecular Weight:
102.13
Molecular Formula:
C5H10O2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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4-Methyl-1,3-dioxane is an acetal derivative. The dioxane ring system, known for its stability and solubility in a variety of organic solvents, can be utilized in synthesizing other cyclic and acyclic compounds, potentially with applications in polymer science and agrochemicals. The characteristics of 4-Methyl-1,3-dioxane, such as its boiling point, polarity, and reactivity, can be leveraged in various chemical reactions, including those requiring specific solvent properties or participating in the formation of cyclic compounds. Additionally, the study of such molecules can provide insights into ring chemistry, particularly how substitutions on heterocyclic compounds affect their behavior and interaction with other chemical entities. 4-Methyl-1,3-dioxane is used in preparation of high-purity 1,3-butylene glycol products.


4-Methyl-1,3-dioxane (CAS 1120-97-4) References

  1. Heterogeneous ceria catalyst with water-tolerant Lewis acidic sites for one-pot synthesis of 1,3-diols via Prins condensation and hydrolysis reactions.  |  Wang, Y., et al. 2013. J Am Chem Soc. 135: 1506-15. PMID: 23228093
  2. Stereochemie der heterocyclen-XXXI: Die konfiguration und bevorzugte konformation substituierter 4-methyl-1,3-dioxane  |  A.W. Bogatskij ∗, Ju.Ju. Samitow, A.I. Gren, S.G. Sobolewa. 1975. Tetrahedron. 31: 489-494.
  3. Microwave spectrum, centrifugal perturbation, dipole moment, and conformation of 4-methyl-1,3-dioxane  |  A. Kh. Mamleev, R. V. Galeev, L. N. Gunderova, M. G. Faizullin & A. A. Shapkin. 2007. Journal of Structural Chemistry. 48: 964–967.
  4. Microwave spectrum, centrifugal perturbation, dipole moment, and conformation of 5-methyl-1,3-dioxane  |  A. Kh. Mamleev, R. V. Galeev, L. N. Gunderova, M. G. Faizullin & A. A. Shapkin. 2008. Journal of Structural Chemistry. 49: 639–64.
  5. Conformational isomerization of 4-methyl-1,3-dioxane  |  A. E. Kuramshina, S. A. Bochkor & V. V. Kuznetsov. 2009. Chemistry of Heterocyclic Compounds. 45: 536–538.
  6. Structure and spectra of 1,3-dioxanes. microwave spectrum, structural parameters, and ab initio calculations of 5-methyl-1,3-dioxane  |  A. Kh. Mamleev, L. N. Gunderova, R. V. Galeev, A. A. Shapkin, M. G. Faizullin, A. P. Nikitina & D. V. Shornikov. 2010. Journal of Structural Chemistry. 51: 238–243.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

4-Methyl-1,3-dioxane, 25 ml

sc-487725
25 ml
$145.00