4-(Fluorosulfonyl)benzoyl chloride (CAS 402-55-1)
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4-(Fluorosulfonyl)benzoyl chloride (4-FSBC) is a chemical reagent used in the synthesis of irreversible adenosine A1 antagonist 8-cyclopentyl-3-N-[3-((3-(4-fluorosulphonyl)benzoyl)-oxy)-propyl]-1-N-propyl-xanthine. Adenosine A1 receptors play a role in various physiological processes, including the modulation of neurotransmitter release, heart rate regulation, and sleep-wake cycle, among others. 4-(Fluorosulfonyl)benzoyl chloride inhibits the enzyme acetylcholinesterase, affecting neurotransmitter regulation in the brain, causes elevated liver enzyme levels, and boosts the production of cytokines and immune markers. It has been used in polymer synthesis, studies of biochemical and physiological processes, research on the effects of organofluorines on the human body, and investigations into the environmental impacts of organofluorines.
4-(Fluorosulfonyl)benzoyl chloride (CAS 402-55-1) References
- An Affinity-Based Probe for the Human Adenosine A2A Receptor. | Yang, X., et al. 2018. J Med Chem. 61: 7892-7901. PMID: 30080404
- Kinetic Optimization of Lysine-Targeting Covalent Inhibitors of HSP72. | Pettinger, J., et al. 2019. J Med Chem. 62: 11383-11398. PMID: 31725295
- MicroRNA detection in biologically relevant media using a split aptamer platform. | Wang, L., et al. 2022. Bioorg Med Chem. 69: 116909. PMID: 35779513
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
4-(Fluorosulfonyl)benzoyl chloride, 1 g | sc-232278 | 1 g | $213.00 |