3′-Deoxyuridine (CAS 7057-27-4)

3′-Deoxyuridine, a nucleoside derivative, has garnered significant interest in biochemical and molecular biology research due to its role in nucleic acid metabolism and DNA synthesis. This compound functions as a precursor in the synthesis of nucleic acids, serving as a substrate for DNA polymerases during DNA replication and repair processes. Research has explaind its mechanism of action, highlighting its involvement in the biosynthesis of DNA and its potential as a modulator of DNA synthesis pathways. Additionally, 3′-Deoxyuridine has been utilized in studies investigating DNA damage and repair mechanisms, providing insights into the cellular responses to genotoxic stress and DNA lesions. Moreover, it serves as a valuable tool in the development of nucleoside analogs for antiviral and anticancer research, with researchers exploring its structural modifications to enhance its efficacy and selectivity against viral and cancerous cells. Furthermore, this chemical compound finds applications in molecular biology techniques such as PCR (Polymerase Chain Reaction) and nucleic acid labeling, facilitating the amplification and detection of specific DNA sequences in research laboratories. Overall, 3′-Deoxyuridine plays a crucial role in advancing our understanding of nucleic acid biochemistry and molecular biology, offering valuable insights into DNA synthesis, repair, and manipulation.