Molecular structure of 3′-Amino-3′-deoxyadenosine, CAS Number: 2504-55-4
3′-Amino-3′-deoxyadenosine (CAS 2504-55-4)
Alternate Names:
3′-AdA; Spalgomycin
CAS Number:
2504-55-4
Purity:
≥97%
Molecular Weight:
266.26
Molecular Formula:
C10H14N6O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
3′-Amino-3′-deoxyadenosine (3-ADA) is an important nucleoside found in ribonucleic acid (RNA). It is a derivative of adenosine and a key component in the synthesis of proteins. It is also involved in the regulation of gene expression and plays a role in the regulation of metabolic processes. In addition, 3′-Amino-3′-deoxyadenosine can act as an inhibitor of certain enzymes involved in the synthesis of proteins.
3′-Amino-3′-deoxyadenosine (CAS 2504-55-4) References
- Syntheses of puromycin from adenosine and 7-deazapuromycin from tubercidin, and biological comparisons of the 7-aza/deaza pair. | Robins, MJ., et al. 2001. J Org Chem. 66: 8204-10. PMID: 11722226
- Isolation and identification of 3'-amino-3'-deoxyadenosine from Cordyceps militaris. | GUARINO, AJ. and KREDICH, NM. 1963. Biochim Biophys Acta. 68: 317-9. PMID: 13951025
- The effect of 3'-amino-3'-deoxyadenosine against ascitic tumors of mice. | PUGH, LH. and GERBER, NN. 1963. Cancer Res. 23: 640-7. PMID: 13972465
- The pur6 gene of the puromycin biosynthetic gene cluster from Streptomyces alboniger encodes a tyrosinyl-aminonucleoside synthetase. | Angel Rubio, M., et al. 2004. FEBS Lett. 577: 371-5. PMID: 15556612
- A luciferase-based screening method for inhibitors of alphavirus replication applied to nucleoside analogues. | Pohjala, L., et al. 2008. Antiviral Res. 78: 215-22. PMID: 18294708
- Formycin 3' end modified tRNATrp. Recognition by avian myeloblastosis virus reverse transcriptase and primer function. | Sarih, L., et al. 1985. Biochem Int. 11: 117-26. PMID: 2412559
- Solution conformational analysis of 2'-amino-2''deoxyadenosine, 3'-amino-3'-deoxyadenosine and puromycin by pulsed nuclear-magnetic-resonance methods. | Plach, H., et al. 1977. Eur J Biochem. 80: 295-304. PMID: 303566
- The preparation of tRNA terminating in 3'-amino-3'-deoxyadenosine and 2'-amino-2'-deoxyadenosine. | Fraser, TH. and Rich, A. 1979. Methods Enzymol. 59: 134-45. PMID: 374935
- Determination of aminoacylation isomeric specificity using tRNA terminating in 3'-amino-3'-deoxyadenosine and 2'-amino-2'-deoxyadenosine. | Fraser, TH., et al. 1979. Methods Enzymol. 59: 272-82. PMID: 374942
- 2',3'-Bis(2-chloroethyl)aminophosphoryl-3'-amino-3'-deoxyadenosine: a cyclic nucleotide with antitumor activity. | Okruszek, A. and Verkade, JG. 1979. J Med Chem. 22: 882-5. PMID: 448687
- Effect of 3'-amino-3'-deoxyadenosine on nucleic acid synthesis in Ehrlich ascites tumor cells. | Truman, JT. and Klenow, H. 1968. Mol Pharmacol. 4: 77-86. PMID: 5640781
- Effect of 3-deoxyadenosine and 3'-amino-3'-deoxyadenosine on the labelling of RNA sub-species in Ehrlich ascites tumor cells. | Truman, JT. and Frederiksen, S. 1969. Biochim Biophys Acta. 182: 36-45. PMID: 5815683
- Nucleoside antibiotics. V. The biosynthesis and interconversion of 3'-amino-3'deoxyadenosine and 3'-acetamido-'3deoxyadenosine by Helminthosporium sp. 215. | Chassy, BM. and Suhadolnik, RJ. 1969. Biochim Biophys Acta. 182: 316-21. PMID: 5815933
- Nascent RNA chain termination and ultrastructural changes in nucleoli isolated from SV40-transformed fibroblasts treated with aminonucleoside of puromycin. | Studzinski, GP. and Albanese, EA. 1980. Lab Invest. 43: 427-33. PMID: 6158625
- Derivatives of 3'- and 5'-deoxyadenosine: their inhibitory activity against DNA viruses. | Grytzmann, B., et al. 1980. Chemotherapy. 26: 316-22. PMID: 6967001
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
3′-Amino-3′-deoxyadenosine, 1 mg | sc-283936 | 1 mg | $153.00 | |||
3′-Amino-3′-deoxyadenosine, 2 mg | sc-283936A | 2 mg | $260.00 | |||
3′-Amino-3′-deoxyadenosine, 5 mg | sc-283936B | 5 mg | $536.00 |