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3-Methyluric Acid (CAS 605-99-2)

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Alternate Names:
N3-Methyluric Acid; 7,9-Dihydro-3-methyl-1H-purine-2,6,8(3H)-trione
CAS Number:
605-99-2
Molecular Weight:
182.14
Molecular Formula:
C6H6N4O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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3-Methyluric acid (3-MU) is a naturally occurring purine compound that holds significance as a intermediate in both animal and plant metabolic pathways. Its role extends beyond intermediacy, as it plays a key part in synthesizing various essential compounds, including drugs, vitamins, and hormones. In terms of metabolic regulation, 3-Methyluric acid exhibits inhibitory effects on specific enzymes, such as xanthine oxidase and aldehyde oxidase. Moreover, it acts as an inhibitor of 5-lipoxygenase, an enzyme involved in the production of pro-inflammatory leukotrienes. As such, 3-Methyluric acid contributes significantly to the modulation of certain metabolic pathways while showcasing its inhibitory potential on key enzymes.


3-Methyluric Acid (CAS 605-99-2) References

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  2. An unusual patient with kidney stones composed of 1-methyluric acid.  |  Davies, PM., et al. 2006. Urol Res. 34: 58-60. PMID: 16397778
  3. Two distinct pathways for metabolism of theophylline and caffeine are coexpressed in Pseudomonas putida CBB5.  |  Yu, CL., et al. 2009. J Bacteriol. 191: 4624-32. PMID: 19447909
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  5. The urinary metabolomic profile following the intake of meals supplemented with a cocoa extract in middle-aged obese subjects.  |  Ibero-Baraibar, I., et al. 2016. Food Funct. 7: 1924-31. PMID: 26961599
  6. Isolation, characterization and application of theophylline-degrading Aspergillus fungi.  |  Zhou, B., et al. 2020. Microb Cell Fact. 19: 72. PMID: 32192512
  7. 3-Methylxanthine production through biodegradation of theobromine by Aspergillus sydowii PT-2.  |  Zhou, B., et al. 2020. BMC Microbiol. 20: 269. PMID: 32854634
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Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

3-Methyluric Acid, 25 mg

sc-500919
25 mg
$359.00

3-Methyluric Acid, 250 mg

sc-500919A
250 mg
$2502.00