3-Deoxy-3-fluoro-D-galactose (CAS 52904-86-6)
QUICK LINKS
3-Deoxy-3-fluoro-D-galactose is a compound that functions as a substrate analog in enzymatic reactions. It is used to study the mechanism of action of enzymes involved in galactose metabolism. 3-Deoxy-3-Fluoro-D-Galactose competitively inhibits the activity of enzymes that utilize D-galactose as a substrate, allowing investigation of specific interactions between the enzyme active site and the substrate. By incorporating 3-Deoxy-3-fluoro-D-galactose into experimental systems can gain insights into the molecular mechanisms of galactose metabolism and related pathways. 3-Deoxy-3-Fluoro-D-Galactose′s mechanism of action involves binding to the active site of the enzyme, thereby interfering with the normal substrate binding and catalytic processes. Through its role as a substrate analog, 3-Deoxy-3-fluoro-D-galactose contributes to the understanding of enzyme kinetics and the development of potential inhibitors for targeted enzymatic pathways.
3-Deoxy-3-fluoro-D-galactose (CAS 52904-86-6) References
- Enzymatic synthesis of UDP-(3-deoxy-3-fluoro)-D-galactose and UDP-(2-deoxy-2-fluoro)-D-galactose and substrate activity with UDP-galactopyranose mutase. | Barlow, JN. and Blanchard, JS. 2000. Carbohydr Res. 328: 473-80. PMID: 11093703
- Structural basis for binding of fluorinated glucose and galactose to Trametes multicolor pyranose 2-oxidase variants with improved galactose conversion. | Tan, TC., et al. 2014. PLoS One. 9: e86736. PMID: 24466218
- A common sugar-nucleotide-mediated mechanism of inhibition of (glycosamino)glycan biosynthesis, as evidenced by 6F-GalNAc (Ac3). | van Wijk, XM., et al. 2015. FASEB J. 29: 2993-3002. PMID: 25868729
- Obtaining Pure 1H NMR Spectra of Individual Pyranose and Furanose Anomers of Reducing Deoxyfluorinated Sugars. | Poškaitė, G., et al. 2023. J Org Chem. 88: 13908-13925. PMID: 37754916
- The use of deoxyfluoro-D-galactopyranoses in a study of yeast galactokinase specificity. | Thomas, P., et al. 1974. Biochem J. 139: 661-4. PMID: 4369372
- Characterization of a novel bacterial adhesion specificity of Streptococcus suis recognizing blood group P receptor oligosaccharides. | Haataja, S., et al. 1993. J Biol Chem. 268: 4311-7. PMID: 8440715
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
3-Deoxy-3-fluoro-D-galactose, 5 mg | sc-216430 | 5 mg | $320.00 |