Date published: 2026-2-12

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3-Chloro-4-fluorophenylboronic acid (CAS 144432-85-9)

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Alternate Names:
(3-Chloro-4-fluorophenyl-1-yl)boronic acid; 3-Chloro-4-fluorobenzeneboronic acid; 4-Fluoro-3-chlorophenylboronic acid
CAS Number:
144432-85-9
Molecular Weight:
174.37
Molecular Formula:
C6H5BClFO2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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3-Chloro-4-fluorophenylboronic acid serves as a versatile reagent in the synthesis of diverse compounds, encompassing agrochemicals, organic compounds, polymers, and other materials. Moreover, it plays a role as a catalyst in various organic reactions, facilitating the synthesis of polymers and other materials. Additionally, its application extends to the synthesis of fluorescent probes utilized in biological imaging. This contains varying amounts of anhydride.


3-Chloro-4-fluorophenylboronic acid (CAS 144432-85-9) References

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  2. Structure-based design, synthesis, and antimicrobial activity of indazole-derived SAH/MTA nucleosidase inhibitors.  |  Li, X., et al. 2003. J Med Chem. 46: 5663-73. PMID: 14667220
  3. Boronolectins and fluorescent boronolectins: an examination of the detailed chemistry issues important for the design.  |  Yan, J., et al. 2005. Med Res Rev. 25: 490-520. PMID: 16025498
  4. Identification of borinic esters as inhibitors of bacterial cell growth and bacterial methyltransferases, CcrM and MenH.  |  Benkovic, SJ., et al. 2005. J Med Chem. 48: 7468-76. PMID: 16279806
  5. Synthesis of 8-thiabicyclo[3.2.1]octanes and their binding affinity for the dopamine and serotonin transporters.  |  Pham-Huu, DP., et al. 2007. Bioorg Med Chem. 15: 1067-82. PMID: 17070057
  6. Synthesis and evaluation of 11C-labeled naphthalene derivative as a novel non-peptidergic probe for the β-secretase (BACE1) imaging in Alzheimer's disease brain.  |  Kawai, T., et al. 2013. Nucl Med Biol. 40: 705-9. PMID: 23706549
  7. Iodine(III)-Mediated, Controlled Di- or Monoiodination of Phenols.  |  Satkar, Y., et al. 2019. J Org Chem. 84: 4149-4164. PMID: 30888169
  8. From Tetrahydrofurans to Tetrahydrobenzo[ d]oxepines via a Regioselective Control of Alkyne Insertion in Rhodium-Catalyzed Arylative Cyclization.  |  Selmani, A., et al. 2019. J Org Chem. 84: 4566-4574. PMID: 30892038
  9. Design and Identification of a Novel, Functionally Subtype Selective GABAA Positive Allosteric Modulator (PF-06372865).  |  Owen, RM., et al. 2019. J Med Chem. 62: 5773-5796. PMID: 30964988
  10. Revisiting Pyrazolo[3,4-d]pyrimidine Nucleosides as Anti-Trypanosoma cruzi and Antileishmanial Agents.  |  Bouton, J., et al. 2021. J Med Chem. 64: 4206-4238. PMID: 33784107

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

3-Chloro-4-fluorophenylboronic acid, 5 g

sc-238516
5 g
$91.00