Date published: 2025-11-3

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(2S,5S)-(+)-1-(2-(1,3-Dioxolan-2-yl)phenyl-2,5-dimethylphospholane (CAS 695816-47-8)

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Alternate Names:
S,S-Me-RajPhos; (2S,5S)-1-[2-(1,3-Dioxolan-2-yl)phenyl]-2,5-dimethylphospholane
Application:
(2S,5S)-(+)-1-(2-(1,3-Dioxolan-2-yl)phenyl-2,5-dimethylphospholane is a highly-effective chiral phospholane ligand
CAS Number:
695816-47-8
Purity:
≥96%
Molecular Weight:
264.30
Molecular Formula:
C15H21O2P
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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(2S,5S)-(+)-1-(2-(1,3-Dioxolan-2-yl)phenyl-2,5-dimethylphospholane (S,S-Me-RajPhos™) is a member of a highly-effective chiral phospholane class of ligands called DuPhos and BPE that contain 2,5-disubstituted groups allowing for systematic variation of the steric environment around the metal. These phospholane ligands can be ligated to metal complexes to afford highly active catalysts for asymmetric hydrogenation and other innovative transformations.


(2S,5S)-(+)-1-(2-(1,3-Dioxolan-2-yl)phenyl-2,5-dimethylphospholane (CAS 695816-47-8) References

  1. Modular phospholane ligands in asymmetric catalysis.  |  Burk, MJ. 2000. Acc Chem Res. 33: 363-72. PMID: 10891054
  2. A Three-Step Procedure for Asymmetric Catalytic Reductive Amidation of Ketones.  |  Burk, MJ., et al. 1998. J Org Chem. 63: 6084-6085. PMID: 11672226

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

(2S,5S)-(+)-1-(2-(1,3-Dioxolan-2-yl)phenyl-2,5-dimethylphospholane, 100 mg

sc-298696
100 mg
$90.00