Molecular structure of 2′-Hydroxyflavanone, CAS Number: 17348-76-4
2′-Hydroxyflavanone (CAS 17348-76-4)
CAS Number:
17348-76-4
Molecular Weight:
240.25
Molecular Formula:
C15H12O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
2′-Hydroxyflavanone is a flavanone compound found in various plants. It is a colorless crystalline solid with a bitter taste. 2′-Hydroxyflavanone is useful due to its antioxidant properties, which make it useful in preventing oxidative damage to cells and biomolecules. 2′-Hydroxyflavanone has anti-inflammatory effects. Its ability to modulate enzyme activity makes it a potential candidate for use in various biochemical assays. 2′-Hydroxyflavanone has potential applications in the industries due to its antioxidant properties. 2′-Hydroxyflavanone has a wide range of potential uses in biochemistry and related fields.
2′-Hydroxyflavanone (CAS 17348-76-4) References
- 2'-hydroxyflavanone inhibits proliferation, tumor vascularization and promotes normal differentiation in VHL-mutant renal cell carcinoma. | Nagaprashantha, LD., et al. 2011. Carcinogenesis. 32: 568-75. PMID: 21304051
- 2'-hydroxyflavanone inhibits prostate tumor growth through inactivation of AKT/STAT3 signaling and induction of cell apoptosis. | Wu, K., et al. 2014. Oncol Rep. 32: 131-8. PMID: 24859932
- 2'-Hydroxyflavanone: A promising molecule for kidney cancer prevention. | Singhal, SS., et al. 2015. Biochem Pharmacol. 96: 151-8. PMID: 25957660
- 2'-Hydroxyflavanone ameliorates mesenteric angiogenesis and portal-systemic collaterals in rats with liver fibrosis. | Hsin, IF., et al. 2016. J Gastroenterol Hepatol. 31: 1045-51. PMID: 26474184
- Hydroxyflavanone inhibits gastric carcinoma MGC-803 cell proliferation. | Zhang, H., et al. 2015. Int J Clin Exp Med. 8: 16955-9. PMID: 26629250
- 2'-Hydroxyflavanone: A novel strategy for targeting breast cancer. | Singhal, J., et al. 2017. Oncotarget. 8: 75025-75037. PMID: 29088842
- 2'-Hydroxyflavanone effectively targets RLIP76-mediated drug transport and regulates critical signaling networks in breast cancer. | Nagaprashantha, LD., et al. 2018. Oncotarget. 9: 18053-18068. PMID: 29719590
- 2'-Hydroxyflavanone inhibits in vitro and in vivo growth of breast cancer cells by targeting RLIP76. | Singhal, J., et al. 2018. Mol Carcinog. 57: 1751-1762. PMID: 30136444
- 2'-Hydroxyflavanone induced changes in the proteomic profile of breast cancer cells. | Nagaprashantha, LD., et al. 2019. J Proteomics. 192: 233-245. PMID: 30248461
- 2'-Hydroxyflavanone activity in vitro and in vivo against wild-type and antimony-resistant Leishmania amazonensis. | Gervazoni, LFO., et al. 2018. PLoS Negl Trop Dis. 12: e0006930. PMID: 30521527
- Topical 2'-Hydroxyflavanone for Cutaneous Melanoma. | Bose, C., et al. 2019. Cancers (Basel). 11: PMID: 31615091
- 2'-Hydroxyflavanone inhibits the progression of pancreatic cancer cells and sensitizes the chemosensitivity of EGFR inhibitors via repressing STAT3 signaling. | Yue, Y., et al. 2020. Cancer Lett. 471: 135-146. PMID: 31811906
- 2'-Hydroxyflavanone prevents LPS-induced inflammatory response and cytotoxicity in murine macrophages. | Sonowal, H. and Ramana, KV. 2020. Toxicol In Vitro. 69: 104966. PMID: 32800949
- Efficacy of 2-Hydroxyflavanone in Rodent Models of Pain and Inflammation: Involvement of Opioidergic and GABAergic Anti-Nociceptive Mechanisms. | Khan, FA., et al. 2022. Molecules. 27: PMID: 36080199
- Analysis of 2'-hydroxyflavanone (2HF) in mouse whole blood by HPLC-MS/MS for the determination of pharmacokinetic parameters. | Gervazoni, LFO., et al. 2023. Front Chem. 11: 1016193. PMID: 36970405
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
2′-Hydroxyflavanone, 1 g | sc-231258 | 1 g | $77.00 |