Molecular structure of 2′-Azido-2′-deoxyuridine, CAS Number: 26929-65-7
2′-Azido-2′-deoxyuridine (CAS 26929-65-7)
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Application:
2′-Azido-2′-deoxyuridine is an antimetabolite that is converted to deoxyuridine triphosphate during DNA syntheis
CAS Number:
26929-65-7
Molecular Weight:
269.21
Molecular Formula:
C9H11N5O5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
2′-Deoxyuridine is an antimetabolite that is converted to deoxyuridine triphosphate during DNA synthesis. Laboratory suppression of deoxyuridine is employed to diagnose megaloblastic anemias due to vitamin B12 and folate deficiencies. 2′-Azido-2′-deoxyuridine is a deoxyuridine derivative. An analogue of zidovudine.
2′-Azido-2′-deoxyuridine (CAS 26929-65-7) References
- Chemical synthesis of site-specifically 2'-azido-modified RNA and potential applications for bioconjugation and RNA interference. | Aigner, M., et al. 2011. Chembiochem. 12: 47-51. PMID: 21171007
- 2'-Azido RNA, a versatile tool for chemical biology: synthesis, X-ray structure, siRNA applications, click labeling. | Fauster, K., et al. 2012. ACS Chem Biol. 7: 581-9. PMID: 22273279
- Site of Azido Substitution in the Sugar Moiety of Azidopyrimidine Nucleosides Influences the Reactivity of Aminyl Radicals Formed by Dissociative Electron Attachment. | Mudgal, M., et al. 2020. J Phys Chem B. 124: 11357-11370. PMID: 33270461
- Incorporation of 2'-amido-nucleosides in oligodeoxynucleotides and oligoribonucleotides as a model for 2'-linked conjugates. | Hendrix, C., et al. 1995. Nucleic Acids Res. 23: 51-7. PMID: 7870590
- Biological activity and phosphorylation of 2'-azido-2'-deoxyuridine and 2'-azido-2'-deoxycytidine. | Kang, SH. and Cho, MJ. 1998. Nucleosides Nucleotides. 17: 1077-88. PMID: 9708323
- Synthesis of 3'-azido-2', 3'-dideoxyribofuranosylpurines | Imazawa, M., & Eckstein, F. 1978. The Journal of Organic Chemistry. 43(15): 3044-3048.
- Conversion of pyrimidine nucleoside 2', 3'-orthoacetates into pyrimidine 2'-azido-2'-deoxynucleosides | Logue, M. W., & Han, B. H. 1980. The Journal of Organic Chemistry. 45(24): 5000-5002.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
2'-Azido-2'-deoxyuridine, 5 mg | sc-220814 | 5 mg | $73.00 |