26S Proteasome Antibody (p32): sc-58311

26S Proteasome Antibody (p32) is a mouse monoclonal IgG1 antibody that detects 26S Proteasome of human origin by western blotting (WB) and immunofluorescence (IF). Anti-26S Proteasome antibody (p32) is available in non-conjugated form. 26S Proteasome plays a crucial role in maintaining cellular homeostasis by selectively degrading ubiquitinated proteins, which is essential for regulating various cellular processes, including cell cycle, apoptosis, and responses to oxidative stress. This proteolytic complex consists of a 20S core particle housing proteolytic activity and a regulatory particle, PA700, facilitating substrate recognition and processing. Precise functioning of 26S Proteasome ensures efficient removal of damaged or misfolded proteins, preventing potential cellular toxicity and contributing to overall cell health. 26S Proteasome also degrades specific transcription factors, such as ERM transcription factor, influencing gene expression and cellular signaling pathways. Using anti-26S Proteasome antibody (p32), researchers can gain insights into protein turnover dynamics and regulatory mechanisms governing cellular function in human tissues.