20S Proteasome α8 Antibody (N-96): sc-130488
- 20S Proteasome α8 Antibody (N-96) is a mouse monoclonal IgG1 κ provided at 50 µg/0.5 ml
- raised against recombinant 20S Proteasome α8 of human origin
- recommended for detection of 20S Proteasome α8 of human origin by WB and IP
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for 20S Proteasome α8 Antibody (N-96). This work is in progress.
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20S Proteasome α8 Antibody (N-96) is a mouse monoclonal IgG1 antibody that detects 20S Proteasome α8 (PSMA8) in human samples through western blotting (WB) and immunoprecipitation (IP) applications. Anti-PSMA8 antibody (N-96) enables researchers to study a crucial component of the 26S proteasome, which maintains cellular homeostasis by degrading unnecessary or damaged proteins through proteolysis. PSMA8 (N-96) monoclonal antibody helps investigate this process, which regulates various cellular functions, including cell cycle, signal transduction, and response to oxidative stress. PSMA8 contributes to proteasome structural integrity and functionality by forming part of the outer rings of the core particle, which consists of multiple α and β subunits. Proper assembly and function of the proteasome prevent misfolded protein accumulation, which can lead to cellular dysfunction and diseases such as cancer and neurodegenerative disorders. Anti-PSMA8 antibody (N-96) helps researchers gain insights into proteasome activity and its implications in various biological processes and disease states.
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20S Proteasome α8 Antibody (N-96) References:
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- cAMP-response element binding protein mediates podocyte injury in diabetic nephropathy by targeting lncRNA DLX6-AS1. | Zheng, W., et al. 2022. Metabolism. 129: 155155. PMID: 35093327
- Fatty acid binding protein 5 promotes the proliferation, migration, and invasion of hepatocellular carcinoma cells by degradation of Krüppel-like factor 9 mediated by miR-889-5p via cAMP-response element binding protein. | Tang, Y., et al. 2022. Cancer Biol Ther. 23: 424-438. PMID: 35816613
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Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
20S Proteasome α8 Antibody (N-96) | sc-130488 | 50 µg/0.5 ml | $339.00 |