Molecular structure of 2-Phthalimidino-glutaric acid, CAS Number: 26577-32-2
2-Phthalimidino-glutaric acid (CAS 26577-32-2)
Application:
2-Phthalimidino-glutaric acid is a stable analog of thalidomide
CAS Number:
26577-32-2
Purity:
≥96%
Molecular Weight:
263.3
Molecular Formula:
C13H13NO5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
2-Phthalimidino-glutaric acid is a stable analog of thalidomide with increased antitumor (antimetastatic) potency.
2-Phthalimidino-glutaric acid (CAS 26577-32-2) References
- Antiangiogenic activity of tumor necrosis factor-alpha production regulators derived from thalidomide. | Shimazawa, R., et al. 1999. Biol Pharm Bull. 22: 224-6. PMID: 10077449
- Synthesis and enantiomeric separation of 2-phthalimidino-glutaric acid analogues: potent inhibitors of tumor metastasis. | Shah, JH., et al. 1999. J Med Chem. 42: 3014-7. PMID: 10447943
- Thalidomide selectively inhibits tumor necrosis factor alpha production by stimulated human monocytes. | Sampaio, EP., et al. 1991. J Exp Med. 173: 699-703. PMID: 1997652
- The effect of thalidomide on experimental tumors and metastases. | Minchinton, AI., et al. 1996. Anticancer Drugs. 7: 339-43. PMID: 8792009
- Inhibition of angiogenesis by thalidomide requires metabolic activation, which is species-dependent. | Bauer, KS., et al. 1998. Biochem Pharmacol. 55: 1827-34. PMID: 9714301
- Thermal and mechanical properties of glycerol-based polymer films infused with plant cell wall polysaccharides | Wyatt, V. T., Yadav, M. P., Latona, N., & Liu, C. K. 2013. Journal of Biobased Materials and Bioenergy. 7(3): 348-356.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
2-Phthalimidino-glutaric acid, 5 mg | sc-220763 | 5 mg | $41.00 | |||
2-Phthalimidino-glutaric acid, 25 mg | sc-220763A | 25 mg | $164.00 |