Date published: 2026-1-21

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2-O-(2-Acetamido-2-deoxy-β-D-glucopyranosyl)-D-mannose (CAS 34621-73-3)

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Alternate Names:
GlcNAc-β-1,2-Man; β-1-2 N-Acetylglucosamine mannose
Application:
2-O-(2-Acetamido-2-deoxy-β-D-glucopyranosyl)-D-mannose is a respiratory pathogen adhesion inhibitor
CAS Number:
34621-73-3
Molecular Weight:
383.35
Molecular Formula:
C14H25NO11
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2-O-(2-Acetamido-2-deoxy-β-D-glucopyranosyl)-D-mannose, a glycoside derivative, has garnered considerable interest in scientific research, particularly in glycobiology and carbohydrate chemistry. Its chemical structure comprises a mannose moiety glycosidically linked to a 2-acetamido-2-deoxy-β-D-glucopyranosyl group at the 2-position. This unique glycoside plays a crucial role in various biological processes, including protein glycosylation, cell-cell recognition, and immune response modulation. Research studies have explaind the role of this glycoside in glycoprotein biosynthesis and quality control within the endoplasmic reticulum and Golgi apparatus. Additionally, its involvement in glycosyltransferase-mediated glycan assembly pathways has been extensively investigated, shedding light on the molecular mechanisms underlying glycan synthesis and diversity. Moreover, 2-O-(2-Acetamido-2-deoxy-β-D-glucopyranosyl)-D-mannose has been utilized as a molecular probe in biochemical assays and structural studies aimed at characterizing glycan-protein interactions and deciphering the molecular basis of carbohydrate recognition by lectins and other carbohydrate-binding proteins. Overall, 2-O-(2-Acetamido-2-deoxy-β-D-glucopyranosyl)-D-mannose serves as a valuable tool in deciphering the complex roles of glycans in biological systems and holds promise for advancing research in glycoscience and related fields.


2-O-(2-Acetamido-2-deoxy-β-D-glucopyranosyl)-D-mannose (CAS 34621-73-3) References

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  2. Adherence of Burkholderia cepacia to respiratory tract epithelial cells and inhibition with dextrans.  |  Chiu, CH., et al. 2001. Microbiology (Reading). 147: 2651-2658. PMID: 11577144
  3. Asialo-GM1 and asialo-GM2 are putative adhesion molecules for Moraxella catarrhalis.  |  Ahmed, K., et al. 2002. Med Microbiol Immunol. 191: 5-10. PMID: 12137200
  4. Genome-based bioinformatic selection of chromosomal Bacillus anthracis putative vaccine candidates coupled with proteomic identification of surface-associated antigens.  |  Ariel, N., et al. 2003. Infect Immun. 71: 4563-79. PMID: 12874336
  5. Structural and functional analysis of four family 84 glycoside hydrolases from the opportunistic pathogen Clostridium perfringens.  |  Pluvinage, B., et al. 2019. Glycobiology. 30: 49-57. PMID: 31701135

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2-O-(2-Acetamido-2-deoxy-β-D-glucopyranosyl)-D-mannose, 1 mg

sc-220753
1 mg
$515.00